Evidence map›Paper›PMID 31477723›Full record

ArticleNature communications2019

Enhanced ion tolerance of electrokinetic locomotion in polyelectrolyte-coated microswimmer.

Xiaojun Zhan, Jizhuang Wang, Ze Xiong, Xuan Zhang, Ying Zhou, Jing Zheng, Jianan Chen, Shien-Ping Feng, Jinyao Tang

Abstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. MOF Coating Enhances the Ion Tolerance of Micromotors.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. Amino acid coating enables micromotor operation in physiological conditions.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Ultrasmall FeNanomaterials (Basel, Switzerland) · 2023
    Article
  15. Medical micro- and nanomotors in the body.Acta pharmaceutica Sinica. B · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. ZnO-based micromotors fueled by CONational science review · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaojun ZhanDepartment of Chemistry, The University of Hong Kong, Hong Kong, 999077, China.
Jizhuang WangDepartment of Chemistry, The University of Hong Kong, Hong Kong, 999077, China.
Ze XiongDepartment of Chemistry, The University of Hong Kong, Hong Kong, 999077, China.ORCID http://orcid.org/0000-0003-4620-6066
Xuan ZhangDepartment of Chemistry, The University of Hong Kong, Hong Kong, 999077, China.
Ying ZhouDepartment of Chemistry, The University of Hong Kong, Hong Kong, 999077, China.
Jing ZhengDepartment of Chemistry, The University of Hong Kong, Hong Kong, 999077, China.
Jianan ChenDepartment of Mechanical Engineering, The University of Hong Kong, Hong Kong, 999077, China.
Shien-Ping FengDepartment of Mechanical Engineering, The University of Hong Kong, Hong Kong, 999077, China.
Jinyao TangDepartment of Chemistry, The University of Hong Kong, Hong Kong, 999077, China. jinyao@hku.hk.ORCID http://orcid.org/0000-0002-0051-148X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last decade, researchers have endeavored to mimic the naturally motile microorganisms and develop artificial nano/microswimmers, which propel themselves in aqueous media. However, most of these nano/microswimmers are propelled by the self-electrophoretic mechanism, which has one critical incompetency: the inability to operate in a high concentration electrolyte solution, such as the most important body fluid, blood. This ionic quenching behavior is well backed by the classical Helmholtz-Smoluchowski theory and seems to be an insurmountable challenge which has shadowed the otherwise promising biomedical applications for artificial nano/microswimmers. Here, we propose that the active nano/microswimmer's self-electrophoresis is fundamentally different from the passive nanoparticle electrophoresis. By significantly increasing the Dukhin number with polyelectrolyte coating and geometry optimization, a favorable deviation from the Helmholtz-Smoluchowski behavior can be realized, and ion tolerance is enhanced by over 100 times for a visible light-powered self-electrophoretic microswimmer.

Identifiers

PMID31477723
PMCPMC6718642

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.