ArticleNature communications2019
Pareto rules for malaria super-spreaders and super-spreading.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Population heterogeneity in Plasmodium vivax relapse risk.PLoS neglected tropical diseases · 2022Trial
- How radical is radical cure? Site-specific biases in clinical trials underestimate the effect of radical cure on Plasmodium vivax hypnozoites.Malaria journal · 2021Trial
- Exploring heterogeneity in mosquito exposure and attraction and its implications for malaria transmission.PLoS computational biology · 2026Article
- The exact mathematical form of the Pareto principle.Theory in biosciences = Theorie in den Biowissenschaften · 2026Article
- A particle-resolved framework for quantifying microbial colonization and vector risk on environmental microplastics.Eco-Environment & Health · 2026Article
- Rare variation in malaria parasites biases population-genetic inference.bioRxiv : the preprint server for biology · 2026Article
- A Fully Expert Human-Based Retrieval Augmented Generation (FEH-RAG) Framework: A Proof of Concept Study in Labelling Patients with Sjögren Syndrome.Medical journal of the Islamic Republic of Iran · 2026Article
- Anopheles stephensi larval habitat superproductivity and its relevance for larval source management in Ethiopia.Malaria journal · 2025Article
- Impact of the intensity of infection in birds on Plasmodium development within Culex pipiens mosquitoes.Parasites & vectors · 2025Article
- The spatial heterogeneity of malaria transmission: An entomological investigation in a highly endemic setting of Burkina Faso.Current research in parasitology & vector-borne diseases · 2025Article
- Disentangling the effects of intermittent faecal shedding and imperfect test sensitivity on the microscopy-based detection of gut parasites in stool samples.PLoS neglected tropical diseases · 2024Article
- À la carte: how mosquitoes choose their blood meals.Trends in parasitology · 2024Review
- Susceptible and infectious states for both vector and host in a dynamic pathogen-vector-host system.Proceedings. Biological sciences · 2024Article
- Economic microbiology: exploring microbes as agents in economic systems.Frontiers in microbiology · 2024Review
- Article
- Evidence for exposure dependent carriage of malaria parasites across the dry season: modelling analysis of longitudinal data.Malaria journal · 2023Article
- Promiscuous feeding on multiple adult honey bee hosts amplifies the vectorial capacity of Varroa destructor.PLoS pathogens · 2023Article
- Individual variation in Plasmodium vivax malaria risk: Are repeatedly infected people just unlucky?PLoS neglected tropical diseases · 2023Review
- Different forms of superspreading lead to different outcomes: Heterogeneity in infectiousness and contact behavior relevant for the case of SARS-CoV-2.PLoS computational biology · 2022Article
- Hotspots and super-spreaders: Modelling fine-scale malaria parasite transmission using mosquito flight behaviour.PLoS pathogens · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
Heterogeneity in transmission is a challenge for infectious disease dynamics and control. An 80-20 "Pareto" rule has been proposed to describe this heterogeneity whereby 80% of transmission is accounted for by 20% of individuals, herein called super-spreaders. It is unclear, however, whether super-spreading can be attributed to certain individuals or whether it is an unpredictable and unavoidable feature of epidemics. Here, we investigate heterogeneous malaria transmission at three sites in Uganda and find that super-spreading is negatively correlated with overall malaria transmission intensity. Mosquito biting among humans is 90-10 at the lowest transmission intensities declining to less than 70-30 at the highest intensities. For super-spreaders, biting ranges from 70-30 down to 60-40. The difference, approximately half the total variance, is due to environmental stochasticity. Super-spreading is thus partly due to super-spreaders, but modest gains are expected from targeting super-spreaders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.