Evidence map›Paper›PMID 31477571›Full record

ArticleDisease models & mechanisms2019

Spz/Toll-6 signal guides organotropic metastasis in

Ketu Mishra-Gorur, Daming Li, Xianjue Ma, Yanki Yarman, Lei Xue, Tian Xu

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  7. Nonautonomous Regulation of Tumor Growth.Advances in experimental medicine and biology · 2025
    Review
  8. Drosophila as a Model for Metastasis.Advances in experimental medicine and biology · 2025
    Review
  9. Functions ofFrontiers in cell and developmental biology · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. International journal of molecular sciences · 2021
    Review
  19. Article
  20. ZnT7 RNAi favors RafOncogene · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ketu Mishra-GorurHoward Hughes Medical Institute, Department of Genetics, Yale University School of Medicine, New Haven, CT 06519, USA ketu.mishra@yale.edu tian.xu@yale.edu.
Daming LiHoward Hughes Medical Institute, Department of Genetics, Yale University School of Medicine, New Haven, CT 06519, USA.
Xianjue MaHoward Hughes Medical Institute, Department of Genetics, Yale University School of Medicine, New Haven, CT 06519, USA.
Yanki YarmanDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT 06519, USA.
Lei XueHoward Hughes Medical Institute, Department of Genetics, Yale University School of Medicine, New Haven, CT 06519, USA.
Tian XuHoward Hughes Medical Institute, Department of Genetics, Yale University School of Medicine, New Haven, CT 06519, USA ketu.mishra@yale.edu tian.xu@yale.edu.ORCID 0000-0002-2160-0027
Howard Hughes Medical Institute · USTongji University · CNYale University · US

Funding

TUMOR SUPPRESSORS AND CELL PROLIFERATION IN DROSOPHILAR01CA069408 · NCI · YALE UNIVERSITY · PI XU, TIAN · 1996 to 2016
$5.1M
NCI NIH HHS R01 CA069408
6 · The paper itself

Abstract

Targeted cell migration plays important roles in developmental biology and disease processes, including in metastasis.

Indexed as

Signal TransductionAnimalsCell Line, TumorDrosophila melanogasterDrosophila ProteinsNeoplasm MetastasisNeoplasmsOrgan SpecificityToll-Like Receptor 6Drosophila Proteinsspz protein, DrosophilaToll-6 protein, DrosophilaToll-Like Receptor 6CancerCell migrationJNKSpätzleToll-like receptorsTumor

Identifiers

PMID31477571
PMCPMC6826028
OpenAlexW2971538765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.