Evidence map›Paper›PMID 31477199›Full record

ArticleeLife2019

Parental vaccination to reduce measles immunity gaps in Italy.

Valentina Marziano, Piero Poletti, Filippo Trentini, Alessia Melegaro, Marco Ajelli, Stefano Merler

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Heterogeneity in social and epidemiological factors determines the risk of measles outbreaks.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Valentina MarzianoCenter for Information Technology, Fondazione Bruno Kessler, Trento, Italy.ORCID 0000-0003-2842-7906
Piero PolettiCenter for Information Technology, Fondazione Bruno Kessler, Trento, Italy.
Filippo TrentiniCenter for Information Technology, Fondazione Bruno Kessler, Trento, Italy.
Alessia MelegaroDepartment of Social and Political Sciences, Bocconi University, Milano, Italy.ORCID 0000-0003-2221-8898
Marco AjelliCenter for Information Technology, Fondazione Bruno Kessler, Trento, Italy.
Stefano MerlerCenter for Information Technology, Fondazione Bruno Kessler, Trento, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-income countries are experiencing measles reemergence as the result of suboptimal vaccine uptake and marked immunity gaps among adults. In 2017, the Italian Government introduced mandatory vaccination at school entry for ten infectious diseases, including measles. However, sustainable and effective vaccination strategies targeting adults are still lacking. We use a data-driven model of household demography to estimate the potential impact on future measles epidemiology of a novel immunization strategy, to be implemented on top of the 2017 regulation, which consists of offering measles vaccine to the parents of children who get vaccinated. Model simulations suggest that the current vaccination efforts in Italy would not be sufficient to interrupt measles transmission before 2045 because of the frequency of susceptible individuals between 17 and 44 years of age. The integration of the current policy with parental vaccination has the potential to reduce susceptible adults by 17-35%, increasing the chance of measles elimination before 2045 up to 78.9-96.5%.

Indexed as

Communicable Diseases, EmergingComputer SimulationDisease Transmission, InfectiousHumansImmunization ProgramsItalyMeaslesMeasles VaccineVaccinationMeasles Vaccineepidemiologyglobal healthimmunity gapsmandatory vaccinationmathematical modelmeasles eliminationparental vaccinationschool entry vaccinationvirus

Identifiers

PMID31477199
PMCPMC6721460

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.