ArticleTheoretical biology & medical modelling2019
A quantitative method for estimating the adaptedness in a physiological study.
Article in Theoretical biology & medical modelling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases.Medicinal research reviews · 2021Review
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Abstract
backgroundExisted mathematical models of individual adaptation are mostly reductionist by nature. Researchers usually a priori consider the subject adapted basing only on the fact of continued or prolonged influence of the harmful factor. This paper describes a method that allows assessing the physiological adaptedness to experimental challenges on the basis of holistic approach and quantitative criteria.
methodsThe suggested method comprises simple equations and incorporates into the model an indicator that differentiates functions in regard to their significance for determining physiological adaptedness considered as an outcome of the adaptive process.
resultsThe proposed empirical model affords the possibility of comparing subjects in respect to their resistance to several loads. Physiological parameters were differentiated with regard to their significance for assessing adaptedness. Two examples of animal adaptation to exercise after physical training and plant adaptogen administration are considered.
conclusionThe calculated index of adaptedness is useful in that it replaces wordy descriptions of large tables that reveal alterations in numerous parameters of many subjects under study.
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