Evidence map›Paper›PMID 31477125›Full record

Observational studyImplementation science : IS2019

Inclusion of a care bundle for fever, hyperglycaemia and swallow management in a National Audit for acute stroke: evidence of upscale and spread.

Tara Purvis, Sandy Middleton, Louise E Craig, Monique F Kilkenny, Simeon Dale, Kelvin Hill, Catherine D'Este, Dominique A Cadilhac

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Implementation science : IS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07627399 (Effectiveness of Implementing Best Care Practices in the Management of Patients With Acute Stroke in Conventional Hospitalization), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07627399 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effectiveness of Implementing Best Care Practices in the Management of Patients With Acute Stroke in Conventional Hospitalization: A Cluster-Randomized, Open, Stepped-Wedge Controlled Trial.

TypeinterventionalSponsorUniversity of MalagaRan2026 to 2028Enrolled700ConditionsStroke, Acute Stroke, Ischemic Stroke, Hemorrhagic StrokeArmsBEST CARE ICTUS_HC BUNDLE
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Six years of the Angels Initiative: Aims, achievements, and future directions to improve stroke care worldwide.International journal of stroke : official journal of the International Stroke Society · 2023
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Tara PurvisStroke and Ageing Research, School of Clinical Sciences at Monash Health, Monash University, Level 3, Hudson Institute Building, 27-31 Wright Street, Clayton, Victoria, 3168, Australia. tara.purvis@monash.edu.ORCID 0000-0003-3332-5357
Sandy MiddletonNursing Research Institute, St Vincent's Health Australia Sydney, St Vincent's Hospital Melbourne, Sydney, New South Wales, Australia.
Louise E CraigNursing Research Institute, St Vincent's Health Australia Sydney, St Vincent's Hospital Melbourne, Sydney, New South Wales, Australia.
Monique F KilkennyStroke and Ageing Research, School of Clinical Sciences at Monash Health, Monash University, Level 3, Hudson Institute Building, 27-31 Wright Street, Clayton, Victoria, 3168, Australia.
Simeon DaleNursing Research Institute, St Vincent's Health Australia Sydney, St Vincent's Hospital Melbourne, Sydney, New South Wales, Australia.
Kelvin HillStroke Division, The Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria, Australia.
Catherine D'EsteNational Centre for Epidemiology and Population Health, Research School of Population Health, ANU College of Health and Medicine, Canberra, Australian Capital Territory, Australia.
Dominique A CadilhacStroke and Ageing Research, School of Clinical Sciences at Monash Health, Monash University, Level 3, Hudson Institute Building, 27-31 Wright Street, Clayton, Victoria, 3168, Australia.
Bond University · AUFlorey Institute of Neuroscience and Mental Health · AUSt Vincent's Hospital Melbourne · AUACT GovernmentHudson Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the Quality in Acute Stroke Care (QASC) trial undertaken in stroke units (SUs) located in New South Wales (NSW), Australia (2005-2010), facilitated implementation of a nurse-led care bundle to manage fever, hyperglycaemia and swallowing (FeSS protocols) reduced death and disability for patients with stroke. We aimed to determine subsequent adherence to the bundled FeSS processes (reflective of the protocols) between 2013 and 2017 in Australian hospitals, and examine whether changes in adherence to these processes varied based on previous participation in the QASC trial or subsequent statewide scale-up (QASCIP-Quality in Acute Stroke Care Implementation Project) and presence of an SU.

methodsCross-sectional, observational study using self-reported organisational survey and retrospective clinical audit data from the National Acute Services Stroke Audit (2013, 2015, 2017). Mixed-effects logistic regression was performed with dependent variables: (1) composite outcome measure reflecting compliance with the FeSS protocols and (2) individual FeSS processes, including the year of audit as an independent variable, adjusted for correlation of outcomes within hospital. Separate models including interaction terms between the year of audit and previous participation in QASC/QASCIP and year of audit and SU were also generated.

resultsHospital participation included the following: 2013-124 hospitals, 3741 cases; 2015-112 hospitals, 4087 cases; and 2017-117 hospitals, 4192 cases. An 80% increase in the odds of receiving the composite outcome in 2017 compared to 2013 was found (2013, 30%; 2017, 41%; OR 1.8; 95% CI 1.6, 2.0; p < 0.001). The odds of FeSS adherence from 2013 to 2017 was greater for hospitals that had participated in QASC/QASCIP relative to those that had not (participated OR 2.1; 95% CI 1.7, 2.7; not participated OR 1.6; 95% CI 1.4, 1.8; p = 0.03). Similar uptake in adherence was evident in hospitals with and without an SU between 2013 and 2017.

conclusionThe use of the FeSS protocols within Australia increased from 2013 to 2017 with the inclusion of these care processes in the National Audit. Greater uptake in hospitals previously involved in QASC/QASCIP was evident. Our implementation methods may be useful for other national initiatives for improving access to evidence-based practice.

Indexed as

Clinical ProtocolsCross-Sectional StudiesDeglutition DisordersEvidence-Based PracticeFeverHumansHyperglycemiaNew South WalesPatient Care BundlesQuality of Health CareRetrospective StudiesStrokeAudit and feedbackCare bundlesHealth services researchQuality improvementStroke

Identifiers

PMID31477125
PMCPMC6721322
OpenAlexW2971973477

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.