Evidence map›Paper›PMID 31476115›Full record

ArticleChemical research in toxicology2019

Small Molecule Antipsychotic Aripiprazole Potentiates Ozone-Induced Inflammation in Airway Epithelium.

Adam M Speen, Jessica R Hoffman, Hye-Young H Kim, Yael N Escobar, Grace E Nipp, Meghan E Rebuli, Ned A Porter, Ilona Jaspers

Open access · greenAbstract read
In one paragraph

Article in Chemical research in toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jessica R HoffmanORCID 0000-0002-9560-6413
Hye-Young H KimDepartment of Chemistry and Center for Molecular Toxicology , Vanderbilt University , Nashville , Tennessee 37235 , United States.
Yael N Escobar
Grace E Nipp
Meghan E Rebuli
Ned A PorterDepartment of Chemistry and Center for Molecular Toxicology , Vanderbilt University , Nashville , Tennessee 37235 , United States.
University of North Carolina at Chapel Hill · USVanderbilt University · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
TOXICOLOGYT32ES007126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ILONA JASPERS, Bernard E. Weissman · 1985 to 2026
$13.0M
Ozone, oxysterols, and lung inflammationR01ES028269 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JASPERS, ILONA, PORTER, NED ALLEN · 2018 to 2023
$2.8M
Big Data to Knowledge Training ProgramT32LM012420 · NLM · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FOREST, MARK GREGORY, KOSOROK, MICHAEL R · 2016 to 2019
$1.1M
Ozone, lipid-protein adducts, and biological effectsR21ES024666 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JASPERS, ILONA, PORTER, NED ALLEN · 2015 to 2016
$437k
NIEHS NIH HHS P30 ES010126NIEHS NIH HHS R01 ES028269NIEHS NIH HHS R21 ES024666NIEHS NIH HHS T32 ES007126NLM NIH HHS T32 LM012420
6 · The paper itself

Abstract

Inhaled ground level ozone (O

Indexed as

Antipsychotic AgentsAripiprazoleCells, CulturedEpithelial CellsHumansInflammationMolecular StructureOzoneRespiratory MucosaSmall Molecule Librariestrans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane DihydrochlorideAntipsychotic AgentsAripiprazoleOzoneSmall Molecule Librariestrans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

Identifiers

PMID31476115
PMCPMC7053648
OpenAlexW2971866739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.