Evidence map›Paper›PMID 31476109›Full record

ArticleCancer medicine2019

Does marital status impact postoperative survival in patients with less differentiated hepatocellular carcinoma? A population-based study.

Bing Yan, Dou-Sheng Bai, Jian-Jun Qian, Chi Zhang, Sheng-Jie Jin, Guo-Qing Jiang

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bing YanDepartment of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Dou-Sheng BaiDepartment of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Jian-Jun QianDepartment of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Chi ZhangDepartment of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Sheng-Jie JinDepartment of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Guo-Qing JiangDepartment of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.ORCID 0000-0002-8699-6624
Yangzhou University · CNDalian Medical University · CN

Funding

Science, Technology and Education: Jiangsu Provincial Medical Youth Talent QNRC2016331
6 · The paper itself

Abstract

backgroundMarital status has long been widely recognized as a determinant of cancer survival. However, only few analytical studies have been conducted on this issue considering heterogeneous factors. The aim of this study was to assess the effects of marital status on postoperative survival of patients with less differentiated (poor/anaplastic) hepatocellular carcinoma (HCC).

methodsWe retrospectively analyzed 1581 postoperative patients diagnosed with poor/anaplastic HCC from the Surveillance, Epidemiology, and End Results database between 2004 and 2015. Patients were classified into married, never married, divorced/separated and widowed groups. Kaplan-Meier analysis and multivariate Cox regression analysis were used to analyze the effects of marital status on HCC cause-specific survival (HCSS).

resultsCompared with married patients, there were no significant differences in HCSS for unmarried, never married, divorced/separated and widowed patients both in univariate (5-year HCSS: 36.0% vs 36.3%, 36.0% vs 32.4%, 36.0% vs 40.2%, 36.0% vs 36.3%, respectively, all P > .05) and multivariate analysis (all P > .05). Furthermore, in stratified analyses according to sex, age, and tumor size, compared with married patients, there were also no significant differences for never married, divorced/separated, and widowed patients both in univariate (all P > .05) and multivariate analysis (all P > .05).

conclusionsFor patients with poor/anaplastic differentiated HCC treated with surgical resection, marital status has no prognostic role in survival.

Indexed as

Marital StatusAdultAgedCarcinoma, HepatocellularCombined Modality TherapyFemaleHumansKaplan-Meier EstimateLiver NeoplasmsMaleMiddle AgedNeoplasm GradingNeoplasm StagingPopulation SurveillanceSEER ProgramSurvival Ratehepatocellular carcinomaless differentiatedmarital statusSEERsurvival

Identifiers

PMID31476109
PMCPMC6797572
OpenAlexW2970111476

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.