Evidence map›Paper›PMID 31475812›Full record

ReviewRevista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia2019

Update on the management of febrile neutropenia in hematologic patients.

F Escrihuela-Vidal, J Laporte, A Albasanz-Puig, C Gudiol

Registry-linked trialAbstract readReview
In one paragraph

Review in Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05133310 (Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05133310 phase4unknown statusnot on this mapstarted 2021, after this paper: background citation

Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia

TypeinterventionalSponsorHospital General de MexicoRan2021 to 2023Enrolled108ConditionsStrains, Acute Lymphoblastic Leukemia, SepsisArmsSimvastatin
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Long-acting granulocyte colony-stimulating factor in primary prophylaxis of early infection in patients with newly diagnosed multiple myeloma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Trial
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Review
  8. Article
  9. Anorectal Pathologies in the Course of Acute Leukaemias; Predictive Parameters.Mediterranean journal of hematology and infectious diseases · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

F Escrihuela-Vidal
J Laporte
A Albasanz-Puig
C GudiolCarlota Gudiol, Infectious Diseases Department, Bellvitge University Hospital. Feixa Llarga s/n, 08907, L'Hospitalet de Llobregat, Barcelona, Spain. cgudiol@iconcologia.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Febrile neutropenia is a common complication in patients with hematologic malignancies receiving chemotherapy, and is associated with high morbidity and mortality. Infections caused by multidrug-resistant bacteria represent a therapeutic challenge in this high-risk patient population, since inadequate initial empirical antibiotic treatment can seriously compromise prognosis. Besides, reducing antimicrobial exposure is a cornerstone in the fight against resistance.

Indexed as

Antineoplastic AgentsDrug Resistance, BacterialDrug Resistance, Multiple, BacterialFebrile NeutropeniaHematologic NeoplasmsHumansImmunocompromised HostAntineoplastic Agents

Identifiers

PMID31475812
PMCPMC6755372

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.