Evidence map›Paper›PMID 31475509›Full record

ArticleJournal of clinical research in pediatric endocrinology2020

Assessment of Bisphenol A Levels in Preschool Children: Results of a Human Biomonitoring Study in Ankara, Turkey

İsmet Çok, Özlem Toprak İkidağ, Dilek Battal, Ayça Aktaş

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical research in pediatric endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

İsmet ÇokGazi University Faculty of Pharmacy, Department of Toxicology, Ankara, TurkeyORCID 0000-0003-3128-677X
Özlem Toprak İkidağGazi University Faculty of Pharmacy, Department of Toxicology, Ankara, TurkeyORCID 0000-0002-1627-3113
Dilek BattalMersin University Faculty of Pharmacy, Department of Toxicology, Mersin, TurkeyORCID 0000-0003-1935-5330
Ayça AktaşMersin University Faculty of Pharmacy, Department of Toxicology, Mersin, TurkeyORCID 0000-0003-3069-7905
Gazi University · TROwl Research Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: There is general concern regarding environmental chemical exposure and the impact it may have on human health. This is particularly important for vulnerable populations such as infants and children during critical periods of development. Bisphenol A (BPA) is an endocrine disrupting chemical used worldwide over the last 30 years in many consumer products. Evidence points to widespread human exposure to BPA. The aim of this study was to evaluate the exposure of Turkish preschool children to BPA. Methods: This study was conducted as a preliminary investigation of BPA in urine, collected from 3-6 year old children living in Ankara. After spot urine samples were taken from preschool children, free BPA, β-D-glucuronide and total BPA were determined using high-performance liquid chromatography tandem mass spectrometry and adjusted by creatinine concentration. Results: Preschool children from Ankara (n=125; males n=70, females n=55; mean age: 4.50±1.26) were recruited. BPA was detected in 76.8% of children from Ankara city, with urinary concentrations ranging from < limit of quantification to 18.36 μg/g creatinine. Total BPA levels were not statistically different between boys (1.26 μg/g creatinine) and girls (2.24 μg/g creatinine) (p>0.05). Conclusion: This study is an important contribution to the limited information about childhood exposure to BPA. The estimated daily BPA intake in this study is substantially lower than the European Food Safety Authority derived tolerable daily intake of 4 μg/kg BW/day.

Indexed as

Biological MonitoringBenzhydryl CompoundsBisphenol A CompoundsChildChild, PreschoolCross-Sectional StudiesEndocrine DisruptorsFemaleHumansMalePhenolsTurkeyBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEndocrine DisruptorsPhenolsBisphenol Achildrenliquid chromatography-mass spectrometryTurkeyurine

Identifiers

PMID31475509
PMCPMC7127886
OpenAlexW2972003620

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.