Evidence map›Paper›PMID 31475276›Full record

ArticleJournal of materials chemistry. B2019

Polyphenol-based nanoplatform for MRI/PET dual-modality imaging guided effective combination chemotherapy.

Jingjing Wang, Wei Sang, Zhen Yang, Zheyu Shen, Zhantong Wang, Orit Jacobson, Yundai Chen, Yong Wang, Mingyan Shao, Gang Niu and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of materials chemistry. B, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 5 countries.

Jingjing WangDepartment of Cardiology, Chinese PLA General Hospital, Beijing 100853, China and Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892, USA. shawn.chen@nih.gov.
Wei SangCancer Centre, Faculty of Health Sciences, University of Macau, Macau SAR 999078, China. yldai@um.edu.mo and Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau SAR 999078, China.
Zhen YangLaboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892, USA. shawn.chen@nih.gov.
Zheyu ShenLaboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892, USA. shawn.chen@nih.gov.ORCID 0000-0002-0350-375X
Zhantong WangLaboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892, USA. shawn.chen@nih.gov.
Orit JacobsonLaboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892, USA. shawn.chen@nih.gov.
Yundai ChenDepartment of Cardiology, Chinese PLA General Hospital, Beijing 100853, China.
Yong WangSchool of Life Science, Beijing University of Chinese Medicine, Beijing 100029, China.
Mingyan ShaoSchool of Life Science, Beijing University of Chinese Medicine, Beijing 100029, China.
Gang NiuLaboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892, USA. shawn.chen@nih.gov.
Yunlu DaiCancer Centre, Faculty of Health Sciences, University of Macau, Macau SAR 999078, China. yldai@um.edu.mo and Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau SAR 999078, China.ORCID 0000-0003-4023-7320
Xiaoyuan ChenLaboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892, USA. shawn.chen@nih.gov.ORCID 0000-0002-9622-0870
National Institutes of Health · USBeijing University of Chinese Medicine · CNUniversity of Macau · MOChinese PLA General Hospital · CN

Funding

Laboratory of Molecular Imaging and NanomedicineZIAEB000073 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI CHEN, XIAOYUAN · 2010 to 2020
$32.8M
Intramural NIH HHS Z99 EB999999Intramural NIH HHS ZIA EB000073
6 · The paper itself

Abstract

Combination therapy with multiple chemotherapeutic agents is the main approach for cancer treatment in the clinic. Polyphenol-based materials are found in our diet, demonstrate good biocompatibility, and prevent numerous diseases. In this study, we encapsulate two drugs in a single polyphenol-based polymer with Fe

Indexed as

Antineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsCell Line, TumorCell SurvivalDoxorubicinDrug CarriersDrug LiberationHumansNanoparticlesNeoplasmsPolyethylene GlycolsSimvastatinTheranostic NanomedicineAntineoplastic AgentsDoxorubicinDrug CarriersPolyethylene GlycolsSimvastatin

Identifiers

PMID31475276
PMCPMC6760993
OpenAlexW2969291599

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.