ArticleAnnals of translational medicine2019
Effect of sevoflurane and propofol on acute kidney injury in pediatric living donor liver transplantation.
Article in Annals of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Pediatric Postoperative Acute Kidney Injury After Noncardiac Surgery: A Systematic Review and Meta-Analysis.Paediatric anaesthesia · 2026Pooled it
- Trial
- Interpreting perioperative oliguria during sevoflurane anesthesia: excretory physiology, fluid responsiveness, and renal endpoints.Journal of anesthesia · 2026Review
- Molecular mechanism of propofol in reducing kidney injury induced by autologous orthotopic liver transplantation.Frontiers in immunology · 2026Article
- Effect of sevoflurane-based or propofol-based anesthesia on acute kidney injury after surgery for gastric cancer: a retrospective propensity score-matched analysis.BMC anesthesiology · 2025Article
- Influence of sevoflurane combined with propofol anesthesia on the anesthesia effect and adverse reactions in children with acute appendicitis.Open medicine (Warsaw, Poland) · 2025Article
- Early sevoflurane sedation in severe COVID-19-related lung injury patients. A pilot randomized controlled trial.Annals of intensive care · 2024Article
- The Effect of Sevoflurane and Propofol on the Status of Renal Complications in Traumatic Injury Patients Following Laminectomy Surgery.Bulletin of emergency and trauma · 2024Article
- Incidence and Risk Factors of Acute Kidney Injury in Pediatric Liver Transplant Patients: A Retrospective Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Experimental and Clinical Aspects of Sevoflurane Preconditioning and Postconditioning to Alleviate Hepatic Ischemia-Reperfusion Injury: A Scoping Review.International journal of molecular sciences · 2023Article
- Effect of Propofol versus Sevoflurane Anesthesia on Acute Kidney Injury after Lung Transplantation Surgery: A Prospective Randomized Controlled Trial.Journal of clinical medicine · 2022Article
- Influence of anesthesia type on post-reperfusion syndrome during liver transplantation: a single-center retrospective study.Anesthesia and pain medicine · 2022Article
- Sevoflurane preconditioning prevents acute renal injury caused by ischemia-reperfusion in mice via activation of the Nrf2 signaling pathway.Experimental and therapeutic medicine · 2022Article
- Continuous Renal Replacement Therapy in Pediatric Patients With Acute Kidney Injury After Liver Transplantation.Frontiers in pediatrics · 2022Article
- The impact of total intravenous anesthesia versus inhalation anesthesia on acute kidney injury after major abdominal surgery: a propensity score analysis.Journal of anesthesia · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute kidney injury (AKI) is the primary cause of morbidity and mortality after major abdominal surgery. However, little is known about the effect of anesthetics on the development of AKI after pediatric liver transplantation (LT). This study aimed to compare the effects of propofol and sevoflurane anesthetics on postoperative AKI after LT surgery.
methodsA total of 120 pediatric patients scheduled for pediatric LT were randomly assigned to receive either continuous infusion of propofol or inhalation of sevoflurane. Serum creatinine (Scr), inflammatory medium and oxidative stress factors and renal biomarkers were measured before surgery (T1), 5 min after anhepatic phase (T2), 10 min after ischemia reperfusion (T3), 2 h after ischemia reperfusion (T4), 24 h after surgery (T5), and 3 d after surgery (T6) to evaluate the effects of anesthetics on the development of postoperative AKI.
resultsThe incidence of AKI was lower in patients receiving sevoflurane than those receiving propofol. The mean arterial pressure was changed slightly in sevoflurane group. The inflammatory factors of interleukin-18, tumor necrosis factor-α, and the levels of neutrophil gelatinase-associated lipocalin (NGAL) were lower in sevoflurane group, while no oxidative stress factors [hydrogen peroxide (H
conclusionsAnesthesia with sevoflurane may be associated with a modest decrease in the incidence of AKI when compared with propofol. Further clarification with relevance to such association is warranted.
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