Evidence map›Paper›PMID 31475077›Full record

ArticleCurrent dermatology reports2019

Updates on Treatment Approaches for Cutaneous Field Cancerization.

Alisen Huang, Julie K Nguyen, Evan Austin, Andrew Mamalis, Jared Jagdeo

Open access · hybridAbstract read
In one paragraph

Article in Current dermatology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Method of Assessing Skin Cancerization and KeratosesClinical and experimental dermatology · 2022
    Article
  11. Article
  12. Protective effects of sunscreen (50+) and octatrienoic acid 0.1% in actinic keratosis and UV damages.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2022
    Article
  13. Review
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alisen HuangDepartment of Dermatology, State University of New York, Downstate Medical Center, Brooklyn, NY, USA.
Julie K NguyenDepartment of Dermatology, State University of New York, Downstate Medical Center, Brooklyn, NY, USA.
Evan AustinDepartment of Dermatology, State University of New York, Downstate Medical Center, Brooklyn, NY, USA.
Andrew MamalisDepartment of Dermatology, State University of New York, Downstate Medical Center, Brooklyn, NY, USA.
Jared JagdeoDepartment of Dermatology, State University of New York, Downstate Medical Center, Brooklyn, NY, USA.
SUNY Downstate Health Sciences University · USState University of New York · US

Funding

Light Emitting Diod-Red Light Phototherapy for Skin FibrosisK23GM117309 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JAGDEO, JARED R · 2016 to 2019
$777k
NIGMS NIH HHS K23 GM117309
6 · The paper itself

Abstract

purpose of reviewField cancerization describes the phenomenon that multiple heterogenous mutations may arise in an area exposed to chronic carcinogenic stimuli. Advances in the understanding of cutaneous field cancerization have led to novel therapeutic approaches to the management of actinic keratoses (AKs). Herein, we review the literature on the pathophysiology and emerging research of field cancerization in dermatology. RECENT

findingsThe classification systems for grading AK lesions are being refined with investigations focusing on their clinical utility. There is a growing shift towards field-directed treatment for AKs as the importance of field cancerization becomes clearer. Current field-directed therapies are being optimized and novel therapeutic modalities are being studied. SUMMARY: Field cancerization underlies the transformation of photodamaged skin into AKs and potentially cutaneous SCC (cSCC). Clinically meaningful classification systems for AKs are needed to better inform decisions regarding treatment. As we learn more about the role of field characterization in photodamage, AKs and cSCCs, therapeutic strategies are becoming more field-directed rather than lesion-directed.

Indexed as

actinic keratosiscutaneous squamous cell carcinomaField cancerizationphotodamagephotodynamic therapy

Identifiers

PMID31475077
PMCPMC6716609
OpenAlexW2963347122

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.