Evidence map›Paper›PMID 31475020›Full record

ArticleFrontiers in plant science2019

siRNA-Finder (si-Fi) Software for RNAi-Target Design and Off-Target Prediction.

Stefanie Lück, Tino Kreszies, Marc Strickert, Patrick Schweizer, Markus Kuhlmann, Dimitar Douchkov

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 168 citations in OpenAlex.

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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Stefanie LückLeibniz Institute of Plant Genetics and Crop Plant Research, Seeland, Germany.
Tino KresziesInstitute of Cellular and Molecular Botany, University of Bonn, Bonn, Germany.
Marc StrickertPhysics II Institute, University of Giessen, Giessen, Germany.
Patrick SchweizerLeibniz Institute of Plant Genetics and Crop Plant Research, Seeland, Germany.
Markus KuhlmannLeibniz Institute of Plant Genetics and Crop Plant Research, Seeland, Germany.
Dimitar DouchkovLeibniz Institute of Plant Genetics and Crop Plant Research, Seeland, Germany.
Leibniz Institute of Plant Genetics and Crop Plant Research · DEUniversity of Bonn · DEUniversity of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA interference (RNAi) is a technique used for transgene-mediated gene silencing based on the mechanism of posttranscriptional gene silencing (PTGS). PTGS is an ubiquitous basic biological phenomenon involved in the regulation of transcript abundance and plants' immune response to viruses. PTGS also mediates genomic stability by silencing of retroelements. RNAi has become an important research tool for studying gene function by strong and selective suppression of target genes. Here, we present

Indexed as

off-targetposttranscriptional gene silencingRNAi designRNAi efficiency predictionRNA interfacesi-Fi

Identifiers

PMID31475020
PMCPMC6704232
OpenAlexW2963035360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.