Evidence map›Paper›PMID 31475014›Full record

ArticleFrontiers in immunology2019

IL-4 Mediated Resistance of BALB/c Mice to Visceral Leishmaniasis Is Independent of IL-4Rα Signaling via T Cells.

Emma McFarlane, Thabang Mokgethi, Paul M Kaye, Ramona Hurdayal, Frank Brombacher, James Alexander, Katharine C Carter

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Emma McFarlaneStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
Thabang MokgethiStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
Paul M KayeDepartment of Biology, Centre for Immunology and Infection, Hull York Medical School, University of York, York, United Kingdom.
Ramona HurdayalInternational Centre for Genetic Engineering and Biotechnology, Cape Town Component, Cape Town, South Africa.
Frank BrombacherInternational Centre for Genetic Engineering and Biotechnology, Cape Town Component, Cape Town, South Africa.
James AlexanderStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
Katharine C CarterStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
University of Strathclyde · GBUniversity of Cape Town · ZAUniversity of York · GB

Funding

Medical Research Council G0400786Medical Research Council G1000230Wellcome Trust
6 · The paper itself

Abstract

Previous studies infecting global IL-4Rα

Indexed as

AnimalsCD4-Positive T-LymphocytesCricetinaeInterleukin-13Interleukin-4Interleukin-4 Receptor alpha SubunitLeishmania majorLeishmaniasis, VisceralMacrophagesMiceMice, Inbred BALB CMice, KnockoutNeutrophilsReceptors, Cell SurfaceSignal TransductionIl4 protein, mouseIl4ra protein, mouseInterleukin-13Interleukin-4Interleukin-4 Receptor alpha SubunitReceptors, Cell SurfaceIL-4IL-4RαLeishmania donovanimiceT cell

Identifiers

PMID31475014
PMCPMC6707061
OpenAlexW2964991854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.