ReviewFrontiers in immunology2019
Trans-generational Immune Priming in Invertebrates: Current Knowledge and Future Prospects.
Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed.
- Is the developmental stage important for the plasticity of transgenerational immune priming?Biology open · 2026Article
- Article
- Rethinking Disease Control in Aquaculture Invertebrates: Harnessing Innate Immunity in Molluscs and Crustaceans.Pathogens (Basel, Switzerland) · 2026Review
- Parental fasting effects on offspring immune gene expression, epigenetic patterns, and gut microbiota in a species with male pregnancy (Syngnathus typhle).BMC biology · 2026Article
- Accumulation and transmission dynamics of 'Candidatus liberibacter solanacearum' haplotypes A and B by potato psyllid nymphs: bioassay and transcriptomic insights.Molecular biology reports · 2026Article
- Toward Understanding and Halting Legacies of Trauma.Biological psychiatry · 2025Review
- Transgenerational pathogen effects: Maternal pathogen exposure reduces offspring fitness.Ecology · 2025Article
- Tetracycline has no long-term effects on gut physiology and microbiome of the new world screwworm, Cochliomyia hominivorax, which has positive implications for transgenic male-only rearing systems.G3 (Bethesda, Md.) · 2025Article
- Improving the odds of survival: transgenerational effects of infections.EMBO molecular medicine · 2025Review
- Multigenerational inheritance of parasitic stress memory inEnvironmental epigenetics · 2025Article
- Evidence for trans-generational immune priming againstFrontiers in immunology · 2025Article
- What Veterinarians Need to Know About the Newly-Emerging Field of Insects-as-Food-and-Feed.Veterinary sciences · 2024Review
- Defensive tactics: lessons from Drosophila.Biology open · 2024Review
- Parent-Specific Transgenerational Immune Priming Enhances Offspring Defense-Unless Heat Stress Negates It All.Ecology and evolution · 2024Article
- Article
- Invertebrate Immunity, Natural Transplantation Immunity, Somatic and Germ Cell Parasitism, and Transposon Defense.International journal of molecular sciences · 2024Review
- Legacies of salient environmental experiences-insights from chemosensation.Chemical senses · 2024Article
- Metabolism and immune memory in invertebrates: are they dissociated?Frontiers in immunology · 2024Review
- Infection risk by oral contamination does not induce immune priming in the mealworm beetle (Frontiers in immunology · 2024Article
- Pathogens and Passengers: Roles for Crustacean Zooplankton Viruses in the Global Ocean.Microorganisms · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trans-generational immune priming (TGIP) refers to the transfer of the parental immunological experience to its progeny. This may result in offspring protection from repeated encounters with pathogens that persist across generations. Although extensively studied in vertebrates for over a century, this phenomenon has only been identified 20 years ago in invertebrates. Since then, invertebrate TGIP has been the focus of an increasing interest, with half of studies published during the last few years. TGIP has now been tested in several invertebrate systems using various experimental approaches and measures to study it at both functional and evolutionary levels. However, drawing an overall picture of TGIP from available studies still appears to be a difficult task. Here, we provide a comprehensive review of TGIP in invertebrates with the objective of confronting all the data generated to date to highlight the main features and mechanisms identified in the context of its ecology and evolution. To this purpose, we describe all the articles reporting experimental investigation of TGIP in invertebrates and propose a critical analysis of the experimental procedures performed to study this phenomenon. We then investigate the outcome of TGIP in the offspring and its ecological and evolutionary relevance before reviewing the potential molecular mechanisms identified to date. In the light of this review, we build hypothetical scenarios of the mechanisms through which TGIP might be achieved and propose guidelines for future investigations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.