ArticleFrontiers in microbiology2019
Legitimate and Reliable Determination of the Age-Related Intestinal Microbiome in Young Piglets; Rectal Swabs and Fecal Samples Provide Comparable Insights.
Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- A manually curated pig gut microbiome dataset for precision feeding.Scientific data · 2026Article
- Alleviation of heat stress-induced microbial dysbiosis in pigs through dietary supplementation with vitamins and trace elements.Animal microbiome · 2026Article
- Prevalence of ESBL-associated resistance genes and antimicrobial resistance inFrontiers in veterinary science · 2026Article
- Characterization of fecal bacterial microbiomes according to fecal color, consistency, and sample type in piglets before and after weaning.Frontiers in veterinary science · 2026Article
- Validation of rectal swabbing for total and aerobic gut microbiota study.Microbiology spectrum · 2025Article
- A bi-variate framework to model microbiome resilience in healthy dogs.Frontiers in veterinary science · 2025Article
- Potential of fermented herbal extracts to modulate digestion and gut microbiota during the weaner and fattening period on commercial pig farms.Frontiers in veterinary science · 2025Article
- Analysis of metagenomic data.Nature reviews. Methods primers · 2025Article
- Metagenomic analysis reveals the community composition of the microbiome in different segments of the digestive tract in donkeys and cows: implications for microbiome research.BMC microbiology · 2024Article
- The dynamic distribution of the rectal microbiota in Holstein dairy calves provides a framework for understanding early-life gut health.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Article
- The developing pig respiratory microbiome harbors strains antagonistic to common respiratory pathogens.mSystems · 2024Article
- Exploring the Effect of GastrointestinalAnimals : an open access journal from MDPI · 2024Review
- A non-invasive tool to collect small intestine content in post weaning pigs: validation study.Scientific reports · 2024Article
- A comparative study of the bacterial diversity and composition of nursery piglets' oral fluid, feces, and housing environment.Scientific reports · 2024Article
- Combined Dietary Supplementation ofVeterinary sciences · 2024Article
- Exploratory application of a cannulation model in recently weaned pigs to monitor longitudinal changes in the enteric microbiome across varied porcine reproductive and respiratory syndrome virus (PRRSV) infection statuses.Frontiers in veterinary science · 2024Article
- The potential role of the microbiota in prostate cancer pathogenesis and treatment.Nature reviews. Urology · 2023Review
- Bifidobacteria define gut microbiome profiles of golden lion tamarin (Leontopithecus rosalia) and marmoset (Callithrix sp.) metagenomic shotgun pools.Scientific reports · 2023Article
- Temporal Microbial Dynamics in Feces Discriminate by Nutrition, Fecal Color, Consistency and Sample Type in Suckling and Newly Weaned Piglets.Animals : an open access journal from MDPI · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A prerequisite for reliable microbiota analysis is having an effective and consistent sampling method. Fecal sampling, commonly used to study the intestinal microbiome, might not be suitable in all situations, especially considering the potential difficulties in obtaining fresh feces from young animals. Indeed, this study shows that the success rate of collecting fecal samples from young piglets (<2 weeks of age) was very low. Therefore, we evaluated rectal swabs as an alternative sample type (to feces) for studying porcine microbiome development and performed a comparative analysis of microbiome composition obtained from fresh fecal samples and rectal swabs in 15 healthy piglets at seven (6 piglets) and 20 (9 piglets) days of age. Three samples (fresh feces, rectal swab before and after defecation) were collected from individual piglets and microbiome composition was assessed by 16S rRNA gene sequencing. The results demonstrated that rectal swabs and fecal samples provide similar microbiome composition profiles, with samples clustering predominantly by individual animal rather than sample type. Furthermore, regardless of the sample type, the biological interpretation with respect to microbiota colonization patterns associated with different ages (7 and 20 days) was found to be comparable. Independent of sample type, we observed age-related changes like increasing microbiota diversity and alterations in relative abundances of the phyla
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