Evidence map›Paper›PMID 31474951›Full record

ArticleFrontiers in microbiology2019

Different Gut Microbial Profiles in Sub-Saharan African and South Asian Women of Childbearing Age Are Primarily Associated With Dietary Intakes.

Minghua Tang, Daniel N Frank, Antoinette Tshefu, Adrien Lokangaka, Shivaprasad S Goudar, Sangappa M Dhaded, Manjunath S Somannavar, Audrey E Hendricks, Diana Ir, Charles E Robertson and 5 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01883193 (Women First), which is not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01883193 nacompletednot on this map

Women First: Preconception Maternal Nutrition

TypeinterventionalSponsorUniversity of Colorado, DenverRan2013 to 2019Enrolled7,374ConditionsMaternal Malnutrition, Growth Failure, Mortality, MorbidityArmsComprehensive Maternal Nutrition Intervention
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  13. The gut microbiome in konzo.Nature communications · 2021
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Minghua TangSection of Nutrition, Department of Pediatrics, University of Colorado Denver, Aurora, CO, United States.
Daniel N FrankDivision of Infectious Diseases, School of Medicine, University of Colorado Denver, Aurora, CO, United States.
Antoinette TshefuKinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.
Adrien LokangakaKinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.
Shivaprasad S GoudarKLE Academy of Higher Education and Research's Jawaharlal Nehru Medical College, Belagavi, India.
Sangappa M DhadedKLE Academy of Higher Education and Research's Jawaharlal Nehru Medical College, Belagavi, India.
Manjunath S SomannavarKLE Academy of Higher Education and Research's Jawaharlal Nehru Medical College, Belagavi, India.
Audrey E HendricksDepartment of Mathematical and Statistical Sciences, University of Colorado Denver, Aurora, CO, United States.
Diana IrDivision of Infectious Diseases, School of Medicine, University of Colorado Denver, Aurora, CO, United States.
Charles E RobertsonDivision of Infectious Diseases, School of Medicine, University of Colorado Denver, Aurora, CO, United States.
Jennifer F KempSection of Nutrition, Department of Pediatrics, University of Colorado Denver, Aurora, CO, United States.
Rebecca L LanderSection of Nutrition, Department of Pediatrics, University of Colorado Denver, Aurora, CO, United States.
Jamie E WestcottSection of Nutrition, Department of Pediatrics, University of Colorado Denver, Aurora, CO, United States.
K Michael HambidgeSection of Nutrition, Department of Pediatrics, University of Colorado Denver, Aurora, CO, United States.
Nancy F KrebsSection of Nutrition, Department of Pediatrics, University of Colorado Denver, Aurora, CO, United States.
University of Colorado Denver · USJawaharlal Nehru Medical College · INMinistry of Public Health · CD

Funding

Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
The Global Network and Preconception Maternal NutritionU10HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI KREBS, NANCY F · 2013 to 2017
$5.1M
NICHD NIH HHS U10 HD076474NICHD NIH HHS UG1 HD076474
6 · The paper itself

Abstract

backgroundTo compare and characterize the gut microbiota in women of childbearing age from sub-Saharan Africa (the Democratic Republic of the Congo, DRC) and South Asia (India), in relation to dietary intakes.

methodsWomen of childbearing age were recruited from rural DRC and India as part of the Women First (WF) preconception maternal nutrition trial. Findings presented include fecal 16S rRNA gene-based profiling of women in the WF trial from samples obtained at the time of randomization, prior to initiation of nutrition intervention and to conception.

resultsStool samples were collected from 217 women (DRC

conclusionConsumption of animal-flesh foods and fermented dairy foods were independently associated with the gut microbiota while demographic variables were not, suggesting that diet may have a stronger association with microbiota than demographic characteristics.

Indexed as

Democratic Republic of the CongodietIndiamicrobiotaWomen

Identifiers

PMID31474951
PMCPMC6702451
OpenAlexW2964793031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.