Evidence map›Paper›PMID 31474949›Full record

ArticleFrontiers in microbiology2019

Inactivation of a Mismatch-Repair System Diversifies Genotypic Landscape of

Minjeong Kang, Kangsan Kim, Donghui Choe, Suhyung Cho, Sun Chang Kim, Bernhard Palsson, Byung-Kwan Cho

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Advances in adaptive laboratory evolution applications forSynthetic and systems biotechnology · 2025
    Review
  4. Article
  5. Genetic mutation inmSystems · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Developing rapid growingMetabolic engineering communications · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Minjeong KangDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
Kangsan KimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
Donghui ChoeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
Suhyung ChoDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
Sun Chang KimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
Bernhard PalssonDepartment of Bioengineering, University of California, San Diego, San Diego, CA, United States.
Byung-Kwan ChoDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adaptive laboratory evolution (ALE) is used to find causal mutations that underlie improved strain performance under the applied selection pressure. ALE studies have revealed that mutator populations tend to outcompete their non-mutator counterparts following the evolutionary trajectory. Among them,

Indexed as

adaptive laboratory evolutionEscherichia coligenotype spacemismatch repairphenotype microarray

Identifiers

PMID31474949
PMCPMC6706779

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.