Evidence map›Paper›PMID 31474934›Full record

ArticleFrontiers in neurology2019

Amyotrophic Lateral Sclerosis and Primary Biliary Cirrhosis Overlap Syndrome: Two Cases Report.

Haibo Zhang, Yaling Liu, Zhenfei Li, Na Liang, Xiaomeng Zhou, Xiangyu Nie, Ting Zhang, Weijing Qi

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Emerging Roles of Bile Acids in Neuroinflammation.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haibo ZhangDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Yaling LiuDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Zhenfei LiDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Na LiangDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Xiaomeng ZhouDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Xiangyu NieDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Ting ZhangDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Weijing QiKey Laboratory of Neurology of Hebei Province, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a disease of which the underlying etiology and pathogenesis are unknown. Numerous data indicate an important role of the immune system and mitochondrial function in the disease. Primary biliary cirrhosis (PBC) is an autoimmune liver disease resulting from a combination of genetic and environmental risk factors. Patients with PBC develop innate and adaptive immune reactions against mitochondrial antigens. Therefore, common mechanisms could exist in both diseases. We present two cases of ALS with PBC to explore the relationship between the two diseases from the immunological and mitochondrial aspects. Further attention should be given to immune-modulating therapy in ALS patients.

Indexed as

amyotrophic lateral sclerosisimmunological mechanismmitochondrial mechanismprimary biliary cirrhosisursodeoxycholic acid

Identifiers

PMID31474934
PMCPMC6702657

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.