ArticleFrontiers in neuroscience2019
Brain Structural Correlates of Odor Identification in Mild Cognitive Impairment and Alzheimer's Disease Revealed by Magnetic Resonance Imaging and a Chinese Olfactory Identification Test.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Disparity of smell tests in Alzheimer's disease and other neurodegenerative disorders: a systematic review and meta-analysis.Frontiers in aging neuroscience · 2023Pooled it
- Olfactory dysfunction in aging and neurodegenerative diseases.Ageing research reviews · 2021Pooled it
- The Correlation Between Olfactory Test and Hippocampal Volume in Alzheimer's Disease and Mild Cognitive Impairment Patients: A Meta-Analysis.Frontiers in aging neuroscience · 2021Pooled it
- Association of Odor Identification Ability With Amyloid-β and Tau Burden: A Systematic Review and Meta-Analysis.Frontiers in neuroscience · 2020Pooled it
- The olfactory functional network in the Alzheimer's disease continuum: a resting state fMRI study.Frontiers in aging neuroscience · 2025Article
- Cerebrovascular burden and neurodegeneration linked to 15-year odor identification decline in older adults.Frontiers in aging neuroscience · 2025Article
- Altered functional connectivity of primary olfactory cortex-hippocampus-frontal cortex in subjective cognitive decline during odor stimulation.Human brain mapping · 2024Article
- Olfactory deficit: a potential functional marker across the Alzheimer's disease continuum.Frontiers in neuroscience · 2024Review
- Clinical characteristics and genetic expansion of 46,XY disorders of sex development children in a Chinese prospective study.Endocrine connections · 2023Article
- Functional and structural alterations of dorsal attention network in preclinical and early-stage Alzheimer's disease.CNS neuroscience & therapeutics · 2023Article
- Olfactory function changes and the predictive performance of the Chinese Smell Identification Test in patients with mild cognitive impairment and Alzheimer's disease.Frontiers in aging neuroscience · 2023Article
- International consensus statement on allergy and rhinology: Olfaction.International forum of allergy & rhinology · 2022Review
- The Effects of Brain Magnetic Resonance Imaging Indices in the Association of Olfactory Identification and Cognition in Chinese Older Adults.Frontiers in aging neuroscience · 2022Article
- Brain Structure as a Correlate of Odor Identification and Cognition in Type 2 Diabetes.Frontiers in human neuroscience · 2022Article
- Molecular and Phenotypic Expansion of Alström Syndrome in Chinese Patients.Frontiers in genetics · 2022Article
- The protective impact of education on brain structure and function in Alzheimer's disease.BMC neurology · 2021Article
- Odor Identification and Regional Gray Matter Atrophy in Patients with Alzheimer's Disease, Parkinson's Disease, and the Healthy Elderly: A Cross-Sectional Structural MRI Study.Brain sciences · 2021Article
- Ageing and Olfactory Dysfunction in Trisomy 21: A Systematic Review.Brain sciences · 2021Review
- Diffusion Tensor Imaging Study of Olfactory Identification Deficit in Patients With Mild Cognitive Impairment.Frontiers in aging neuroscience · 2021Article
- Odor Sensitivity Versus Odor Identification in Older US Adults: Associations With Cognition, Age, Gender, and Race.Chemical senses · 2020Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is a common memory-impairment disorder frequently accompanied by olfactory identification (OI) impairments. In fact, OI is a valuable marker for distinguishing AD from normal age-related cognitive impairment and may predict the risk of mild cognitive impairment (MCI)-to-AD transition. However, current olfactory tests were developed based on Western social and cultural conditions, and are not very suitable for Chinese patients. Moreover, the neural substrate of OI in AD is still unknown. The present study investigated the utility of a newly developed Chinese smell identification test (CSIT) for OI assessment in Chinese AD and MCI patients. We then performed a correlation analysis of gray matter volume (GMV) at the voxel and region-of-interest (ROI) levels to reveal the neural substrates of OI in AD. Thirty-seven AD, 27 MCI, and 30 normal controls (NCs) completed the CSIT and MRI scans. Patients (combined AD plus MCI) scored significantly lower on the CSIT compared to NCs [
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.