Evidence map›Paper›PMID 31474364›Full record

ArticleCell2019

A Pungent and Painful Toxin.

Dustin Green, Xinzhong Dong

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Dustin GreenThe Solomon H. Snyder Department of Neuroscience, Department of Neurosurgery, Department of Dermatology, Center for Sensory Biology, Johns Hopkins University, School of Medicine, Baltimore, MD 21205. Electronic address: dgreen89@jhmi.edu.
Xinzhong DongThe Solomon H. Snyder Department of Neuroscience, Department of Neurosurgery, Department of Dermatology, Center for Sensory Biology, Johns Hopkins University, School of Medicine, Baltimore, MD 21205; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205. Electronic address: xdong2@jhmi.edu.
Howard Hughes Medical Institute · USJohns Hopkins University · US

Funding

Isogenic Human Pluripotent Stem Cell-Based Models of Human Disease MutationsR01DK097768 · NIDDK · BROAD INSTITUTE, INC. · PI COWAN, CHAD ALBERT, ZHANG, FENG · 2012 to 2016
$11.0M
Systematic cell-based functional screening for LDL and triglyceride genesR33HL120781 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI COWAN, CHAD ALBERT, KATHIRESAN, SEKAR · 2016 to 2018
$1.6M
The Role of the Mast Cells in Postoperative PainF32GM121030 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREEN, DUSTIN PEPPER · 2016 to 2017
$111k
NHLBI NIH HHS R33 HL120781NIDDK NIH HHS R01 DK097768NIGMS NIH HHS F32 GM121030
6 · The paper itself

Abstract

In this issue of Cell, King et al. (2019) have discovered a cell penetrating peptide isolated from the venom of the Australian Black Rock scorpion that activates the TRPA1 receptor in a unique way to induce pain. Their findings offer new insights into how animals evolved venoms to target specific ion channel functions.

Indexed as

ScorpionsScorpion VenomsAnimalsAustraliaPainPeptidesPeptidesScorpion Venoms

Identifiers

PMID31474364
OpenAlexW2970406603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.