Evidence map›Paper›PMID 31474163›Full record

ArticleInnate immunity2019

NOD1/NOD2-mediated recognition of non-typeable

Jasmine Lee, Anke Leichtle, Emily Zuckerman, Kwang Pak, Meghan Spriggs, Stephen I Wasserman, Arwa Kurabi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Innate immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Dysregulation of immune response in otitis media.Expert reviews in molecular medicine · 2021
    Pooled it
  2. Article
  3. Review
  4. Advances in the Study of NOD-Like Receptors in Common Otological Diseases.The journal of international advanced otology · 2025
    Review
  5. Article
  6. mBio · 2023
    Article
  7. The Roles of NOD-like Receptors in Innate Immunity in Otitis Media.International journal of molecular sciences · 2022
    Review
  8. Immunomodulation as a Protective Strategy in Chronic Otitis Media.Frontiers in cellular and infection microbiology · 2022
    Article
  9. Article
  10. Review
  11. Innate Immunity in the Middle Ear Mucosa.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jasmine LeeDepartment of Surgery, University of California San Diego, USA.
Anke LeichtleDepartment of Surgery, University of California San Diego, USA.
Emily ZuckermanDepartment of Surgery, University of California San Diego, USA.
Kwang PakDepartment of Surgery, University of California San Diego, USA.
Meghan SpriggsDepartment of Surgery, University of California San Diego, USA.
Stephen I WassermanDepartment of Medicine, University of California San Diego, USA.
Arwa KurabiDepartment of Surgery, University of California San Diego, USA.ORCID 0000-0001-5765-9496

Funding

Middle ear responses in Otitis MediaR01DC000129 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RYAN, ALLEN F. · 1989 to 2021
$6.8M
Innovative therapy for diseases of the middle earR01DC012595 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RYAN, ALLEN F. · 2012 to 2023
$3.3M
Mechanisms of Persistence and Recovery in Otitis MediaR01DC006279 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WASSERMAN, STEPHEN I · 2003 to 2014
$3.1M
Establishment of an animal model of human-specific responses to middle ear infection.R03DC014801 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KURABI, ARWA · 2016 to 2018
$465k
NIDCD NIH HHS R01 DC000129NIDCD NIH HHS R01 DC006279NIDCD NIH HHS R01 DC012595NIDCD NIH HHS R03 DC014801
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCells, CulturedDisease Models, AnimalEar, MiddleHaemophilus InfectionsHaemophilus influenzaeHumansImmunity, InnateInflammationMacrophagesMiceMice, Inbred C57BLMice, KnockoutNeutrophilsNod1 Signaling Adaptor ProteinNod2 Signaling Adaptor ProteinNod1 protein, mouseNod1 Signaling Adaptor ProteinNod2 protein, mouseNod2 Signaling Adaptor Proteinautophagycytokinesinflammationmiddle earNORsotitis mediapathogen recognition

Identifiers

PMID31474163
PMCPMC6900663

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.