Evidence map›Paper›PMID 31473907›Full record

Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

A psychometric analysis and revalidation of the Yale-Brown Obsessive Compulsive Scale modified for Binge Eating in adults with binge eating disorder.

Karen Yee, Daniel Serrano, Judith Kando, Susan L McElroy

Abstract readRandomized Controlled TrialValidation Study
In one paragraph

Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karen YeeShire, a member of the Takeda group of companies, Lexington, MA, USA. karen.yee@takeda.com.ORCID http://orcid.org/0000-0002-6026-1435
Daniel SerranoPharmerit International, Bethesda, MD, USA.
Judith KandoShire, a member of the Takeda group of companies, Lexington, MA, USA.
Susan L McElroyLindner Center of HOPE, Mason, OH, USA.ORCID http://orcid.org/0000-0002-8879-0865

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Yale-Brown Obsessive Compulsive Scale modified for Binge Eating (Y-BOCS-BE) assesses the obsessiveness of binge eating thoughts and compulsiveness of binge eating behaviors. The findings of this study extend previously published Y-BOCS-BE psychometric evaluations in adults with binge eating disorder (BED).

methodsData from three phase 3 lisdexamfetamine dimesylate studies in adults with BED (two randomized, double-blind, placebo-controlled short-term efficacy studies; one double-blind, placebo-controlled, randomized-withdrawal maintenance-of-efficacy study) were used. Psychometric evaluations included assessment of Y-BOCS-BE dimensionality, internal consistency, convergent validity, test?retest reliability, and determinations of clinically meaningful improvement using distribution- and anchor-based methods.

resultsDomain specification analyses determined that the Y-BOCS-BE possessed a bifactor structure composed of a general binge eating severity domain and three subdomains (obsessive/compulsive, restraint, and control). Y-BOCS-BE internal consistency was maximized at week 12 (Cronbach?s ?, 0.95) and test?retest reliability was maximized in the 8-week retest interval from week 4 to week 12 across all no-change anchors (r?=?0.74?0.90). Likewise, convergent validity of the Y-BOCS-BE across all validators was maximized at week 12 (all r???0.66). Meaningful improvement for Y-BOCS-BE total scores was estimated to require score reductions of 12 to 17 points depending on the anchor.

conclusionsThe Y-BOCS-BE is a valuable tool for assessing BED symptoms. Maximization of Y-BOCS-BE reliability and validity at later study time points may be related to both treatment effects and improved insight into BED by participants during the study.

Indexed as

Surveys and QuestionnairesAdultBinge-Eating DisorderCentral Nervous System StimulantsConduct DisorderDouble-Blind MethodFemaleHumansLisdexamfetamine DimesylateMaleMiddle AgedObsessive-Compulsive DisorderPsychometricsQuality of LifeReproducibility of ResultsYoung AdultCentral Nervous System StimulantsLisdexamfetamine DimesylateBinge eating disorderCalibrationPsychometricsReliabilityYale-Brown Obsessive Compulsive Scale modified for Binge Eating

Identifiers

PMID31473907
PMCPMC6863951

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.