Evidence map›Paper›PMID 31473779›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2019

The treatment efficacy of nasal polyposis on olfactory functions, clinical scoring systems and inflammation markers.

Zehra Betul Paksoy, Melih Cayonu, Cigdem Yucel, Turan Turhan

Abstract read
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Vitamin D and Interleukins in Chronic Rhinosinusitis with Polyposis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zehra Betul PaksoyDepartment of Otorhinolaryngology, Ankara Numune Training and Research Hospital, Talatpasa Avenue, Ankara, 06100, Turkey.
Melih CayonuDepartment of Otorhinolaryngology, Ankara Numune Training and Research Hospital, Talatpasa Avenue, Ankara, 06100, Turkey. melihcayonu@yahoo.com.ORCID http://orcid.org/0000-0001-5542-1898
Cigdem YucelDepartment of Clinical Biochemistry, Ankara Numune Training and Research Hospital, Ankara, Turkey.
Turan TurhanDepartment of Clinical Biochemistry, Ankara Numune Training and Research Hospital, Ankara, Turkey.
Ankara Numune Eğitim ve Araştırma Hastanesi · TR

Funding

Ankara Numune Egitim ve Arastirma Hastanesi 1214/2017
6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate the effect of the medical and the surgical treatment on the olfactory functions, clinical scoring systems and inflammation markers in patients with nasal polyposis. In addition, the secondary aim was to investigate the correlation between those investigated parameters. SUBJECTS AND

methodsA total of 30 patients, who completed the standardized medical and surgical treatment and also came to 3 months of follow-ups regularly after the surgery, were included in the study. The Sniffin' Sticks olfactory tests, radiological and the endoscopic stagings, liver-expressed chemokine (CCL16) and endothelin (ET) levels and sino-nasal outcome test-22 (SNOT-22) were performed at the initial and at the end of the study.

resultsThe current study had four major findings: (1) significant improvement in odor functions after treatment was determined; however, the majority of the patients had been already hyposmic. (2) In addition, significant improvement was found in ET and CCL16 levels, SNOT-22 results, and radiologic and endoscopic stagings at the end of the study. (3) However, there was no correlation between the olfactory functions and the investigated parameters. (4) There was a positive correlation between polyp recurrence and ET levels.

conclusionThe standardized medical and surgical treatment provided a significant improvement in the olfactory functions. However, only one patient (3.3%) had become normosmic at the end of the study.

Indexed as

AdultBiomarkersChemokines, CCEndoscopyEndothelinsFemaleFollow-Up StudiesHumansInflammationMaleMiddle AgedNasal PolypsOlfaction DisordersOlfactory PerceptionPrednisoloneProspective StudiesBiomarkersCCL16 protein, humanChemokines, CCEndothelinsPrednisoloneCCL16Endoscopic sinus surgeryEndothelinNasal polyposisSniffin’ sticksSNOT-22Steroid treatment

Identifiers

PMID31473779
OpenAlexW2970000709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.