Evidence map›Paper›PMID 31473657›Full record

ArticleJournal of medical ethics2020

Intergenerational monitoring in clinical trials of germline gene editing.

Bryan Cwik

Abstract read
In one paragraph

Article in Journal of medical ethics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Revising, Correcting, and Transferring Genes.The American journal of bioethics : AJOB · 2020
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Bryan CwikPhilosophy and University Studies, Portland State University, Portland, Oregon, USA bcwik@pdx.edu.ORCID 0000-0002-5570-3403

Funding

Intergenerational Monitoring in Clinical Trials of Germline Gene Editing: Ethical, Legal, and Social IssuesR03HG010417 · NHGRI · PORTLAND STATE UNIVERSITY · PI CWIK, BRYAN · 2018 to 2019
$149k
NHGRI NIH HHS R03 HG010417
6 · The paper itself

Abstract

Design of clinical trials for germline gene editing stretches current accepted standards for human subjects research. Among the challenges involved is a set of issues concerning

Indexed as

Gene EditingGerm CellsFollow-Up StudiesHumansMoralsClinical trialsGene Therapy/TransferReproductive MedicineResearch Ethics

Identifiers

PMID31473657
PMCPMC7036322

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.