Evidence map›Paper›PMID 31473618›Full record

ArticleBMJ open2019

The global epidemiology of viral-induced acute liver failure: a systematic review protocol.

Jenna Patterson, Hannah Sophia Hussey, Leila Hussein Abdullahi, Sheetal Silal, Liz Goddard, Mashiko Setshedi, Wendy Spearman, Gregory D Hussey, Benjamin Kagina, Rudzani Muloiwa

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Viral hepatitis-induced acute liver failure.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Jenna PattersonVaccines for Africa Initiative, University of Cape Town, Cape Town, South Africa PTTJEN005@myuct.ac.za.ORCID 0000-0002-3927-037X
Hannah Sophia HusseyVaccines for Africa Initiative, University of Cape Town, Cape Town, South Africa.
Leila Hussein AbdullahiSchool of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
Sheetal SilalDepartment of Statistical Sciences, University of Cape Town, Cape Town, South Africa.
Liz GoddardDepartment of Paediatrics, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.
Mashiko SetshediDepartment of Medicine, Division of Gastroenterology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Wendy SpearmanDepartment of Medicine, Division of Hepatology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Gregory D HusseyVaccines for Africa Initiative, University of Cape Town, Cape Town, South Africa.
Benjamin KaginaVaccines for Africa Initiative, University of Cape Town, Cape Town, South Africa.
Rudzani MuloiwaVaccines for Africa Initiative, University of Cape Town, Cape Town, South Africa.
University of Cape Town · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe burden of viral-induced acute liver failure (ALF) around the world still remains unclear, with little to no data collected regarding the disease incidence in general and synthesised data on the relative contribution of different viruses to the aetiology of ALF is missing in the field. The aim of this review is to estimate the burden (prevalence, incidence, mortality, hospitalisation) of ALF following infection METHODS AND ANALYSIS: EBSCOhost, PubMed, ScienceDirect, Scopus and Web of Science databases will be searched for relevant literature published and grey literature from 2009 up to 2019. Published cross-sectional and cohort studies will be eligible for inclusion in this review. Qualifying studies will be formally assessed for quality and risk of bias using a standardised scoring tool. Following standardised data extraction, meta-analyses will be carried out using STATA. Depending on characteristics of included studies, subgroup analyses and meta-regression analyses will be performed. This review will be reported according to Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. ETHICS AND DISSEMINATION: No ethics approval is required as the systematic review will use only published data already in the public domain. Findings will be disseminated through publication in a peer-reviewed journal. PROSPERO REGISTRATION NUMBER: CRD42018110309.

Indexed as

Global HealthHumansLiver Failure, AcuteMeta-Analysis as TopicResearch DesignSystematic Reviews as TopicVirus Diseasesacute liver failureepidemiologyglobal

Identifiers

PMID31473618
PMCPMC6720318
OpenAlexW2970291365

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.