Evidence map›Paper›PMID 31472332›Full record

SynthesisJournal of anxiety disorders2019

Examining military population and trauma type as moderators of treatment outcome for first-line psychotherapies for PTSD: A meta-analysis.

Casey L Straud, Jedidiah Siev, Stephen Messer, Alyson K Zalta

Registry-linked trialOpen access · greenAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of anxiety disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05876481 (Evaluation of the Acceptability, Safety, Feasibility, and Efficacy of Psilocybin-assisted Psychotherapy), which is not on this map. Cited by 47 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 12 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05876481 phase2unknown statusnot on this mapstarted 2023, after this paper: background citation

Evaluation of the Acceptability, Safety, Feasibility, and Efficacy of Psilocybin-assisted Psychotherapy (PaP) for the Treatment of Post-traumatic Stress Disorder (PTSD) in Military Veterans

TypeinterventionalSponsorCombat StressRan2023 to 2025Enrolled8ConditionsPTSDArmsPsilocybin
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 12 syntheses or guidelines pooled it, 112 citations in OpenAlex.

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  4. A whole-brain voxel-based analysis of structural abnormalities in PTSD: An ENIGMA-PGC study.European psychiatry : the journal of the Association of European Psychiatrists · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Casey L StraudUniversity of Texas Health Science Center at San Antonio, San Antonio, TX, United States. Electronic address: straud@uthscsa.edu.
Jedidiah SievSwarthmore College, Swarthmore, PA, United States.
Stephen MesserNova Southeastern University, Fort Lauderdale, FL, United States.
Alyson K ZaltaUniversity of California, Irvine, Irvine, CA, United States.
Nova Southeastern University · USSwarthmore College · USThe University of Texas Health Science Center at San Antonio · USUniversity of California, Irvine · US

Funding

Using CBT to Probe Psychobiobehavioral Resilience to Post-trauma PsychopathologyK23MH103394 · NIMH · RUSH UNIVERSITY MEDICAL CENTER · PI ZALTA, ALYSON KAY · 2014 to 2018
$769k
NIMH NIH HHS K23 MH103394
6 · The paper itself

Abstract

There is conflicting evidence as to whether military populations (i.e., veteran and active-duty military service members) demonstrate a poorer response to psychotherapy for posttraumatic stress disorder (PTSD) compared to civilians. Existing research may be complicated by the fact that treatment outcomes differences could be due to the type of trauma exposure (e.g., combat) or population differences (e.g., military culture). This meta-analysis evaluated PTSD treatment outcomes as a function of trauma type (combat v. assault v. mixed) and population (military v. civilian). Unlike previous meta-analyses, we focused exclusively on manualized, first-line psychotherapies for PTSD as defined by expert treatment guidelines. Treatment outcomes were large across trauma types and population; yet differences were observed between trauma and population subgroups. Military populations demonstrated poorer treatment outcomes compared to civilians. The combat and assault trauma subgroups had worse treatment outcomes compared to the mixed trauma subgroup, but differences were not observed between assault and combat subgroups. Higher attrition rates predicted poorer treatment outcomes, but did not vary between military populations and civilians. Overall, manualized, first-line psychotherapies for PTSD should continue to be used for civilians and military populations with various trauma types. However, greater emphasis should be placed on enhancing PTSD psychotherapies for military populations and on treatment retention across populations based on findings from this meta-analysis.

Indexed as

PsychotherapyHumansMilitary PersonnelStress Disorders, Post-TraumaticTreatment OutcomeVeteransCiviliansFirst-Line treatmentsMeta-AnalysisMilitaryPosttraumatic stress disorderTrauma typeVeterans

Identifiers

PMID31472332
PMCPMC6739153
OpenAlexW2967952821

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.