ArticleInternational journal of clinical oncology2020
Feasibility of laparoscopic adrenalectomy for metastatic adrenal tumors in selected patients: a retrospective multicenter study of Japanese populations.
Article in International journal of clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 9 citations in OpenAlex.
- Surgical Management of Isolated Adrenal Metastases: A Retrospective Comparative Study of Open, Laparoscopic, and Robotic Adrenalectomy.Journal of clinical medicine · 2026Article
- Comparative outcomes and prognostic indicators in adrenalectomy for adrenal metastasis.Surgical endoscopy · 2024Article
- Metastatic neuroendocrine carcinoma of right adrenal gland successfully treated with laparoscopic adrenalectomy after multimodal therapy.IJU case reports · 2022Article
- Cytomegalovirus adrenalitis mimicking adrenal metastasis in an immunocompetent patient.Journal of surgical case reports · 2022Article
- Outcomes after Surgical Treatment of Metastatic Disease in the Adrenal Gland; Valuable for the Patient?Cancers · 2021Article
- Prognostic factors after adrenalectomy for adrenal metastasis.International urology and nephrology · 2020Article
- Adrenal metastases - long-term results of surgical treatment, single-centre experience.Contemporary oncology (Poznan, Poland) · 2020Article
- Clinical Outcomes of Adrenalectomy for Metastatic Adrenal Tumor: A 30-case Single-center Study.Cancer diagnosis & prognosisArticle
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19 authors at 11 institutions in 1 country.
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Abstract
backgroundBecause of the small numbers of cases in single centers, the indications for and survival benefits of adrenalectomy for adrenal metastasis remain unclear. We evaluated the outcomes of laparoscopic adrenalectomy for patients with adrenal metastasis.
methodsWe retrospectively analyzed the records of 67 patients who underwent laparoscopic adrenalectomy for metastatic disease from 2003 to 2017 at 11 hospitals. Associations of clinical, surgical, and pathologic features with overall survival (OS) and positive surgical margins were evaluated using univariate and multivariate Cox regression analyses and univariate logistic regression analysis.
resultsLung cancer (30%) and renal cell carcinoma (30%) were the most common primary tumor types. Intraoperative complications were observed in seven patients (10%) and postoperative complications in seven (10%). The surgical margin was positive in 10 patients (15%). The median OS was 3.8 years. Univariate analysis showed that the tumor size, episodes of extra-adrenal metastasis before adrenalectomy, extra-adrenal metastasis at the time of adrenalectomy, and positive surgical margins were significantly associated with shorter OS (p = 0.022, p = 0.005, p < 0.001, and p = 0.022, respectively). Multivariate analysis showed that extra-adrenal metastasis at the time of adrenalectomy and positive surgical margins remained statistically significant (p = 0.022 and p = 0.049, respectively). In the univariate analysis, the tumor size was significantly associated with positive surgical margins (p = 0.039).
conclusionsLaparoscopic adrenalectomy for adrenal metastasis can be safely performed in selected patients, and patients with isolated adrenal metastasis and negative surgical margins seem to have more favorable outcomes.
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