ReviewCurrent cardiology reports2019
Cardiovascular Disease and Hair Cortisol: a Novel Biomarker of Chronic Stress.
Review in Current cardiology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
90 citing papers in PubMed, 4 syntheses or guidelines pooled it, 200 citations in OpenAlex.
- Hair cortisol as outcome parameter for psychological and neuropsychiatric interventions-a literature review.Frontiers in psychiatry · 2023Pooled it
- Prevalence and incidence of post-traumatic stress disorder and symptoms in people with chronic somatic diseases: A systematic review and meta-analysis.Frontiers in psychiatry · 2023Pooled it
- A systematic review and meta-analysis of the Everyday Discrimination Scale and biomarker outcomes.Psychoneuroendocrinology · 2022Pooled it
- Chronic Stress A Potential Suspect Zero of Atherosclerosis: A Systematic Review.Frontiers in cardiovascular medicine · 2021Pooled it
- Effects of Olive Oil Consumption on Cardiovascular Risk Factors in Patients with Fibromyalgia.Nutrients · 2020Trial
- Coronary Artery Disease and Loneliness: A Cross-Sectional Analysis using the Revised UCLA Loneliness Scale.The International journal of angiology : official publication of the International College of Angiology, Inc · 2026Article
- Associations between Fear of Crime and Symptom Burden among Non-victimized Older Adults: Findings from the Swedish Population-Based Study "Good Aging in Skåne".Annals of geriatric medicine and research · 2026Article
- Autonomic Modulation and Body Composition in Educators: Physiological Associations in the Workplace Context.Brain and behavior · 2026Article
- Measurement of Hair Cortisol Throughout Gestation.Journal of clinical medicine · 2026Article
- Bias in hair cortisol measures for psychological stress: Self vs. professional collection.Psychoneuroendocrinology · 2026Article
- Sex-specific associations between loneliness and hair cortisol among older African American adults.Psychoneuroendocrinology · 2026Article
- Effects of a year-long aerobic exercise intervention on neuroendocrine, autonomic, and neural correlates of stress, emotion, and cardiovascular disease risk in midlife adults.Journal of sport and health science · 2026Article
- The association between levels of GPS-tracked activity space violent crime and the relationship between cortisol and a biomarker of inflammation amongst Black and White adolescents.Psychoneuroendocrinology · 2026Article
- Non-traditional risk factors for myocardial infarction in adults under forty: A systematic review of emerging trends.World journal of cardiology · 2026Article
- Profiles of stress hormones in relation to DENV serotypes among dengue-positive patients.PloS one · 2026Article
- Linking combined oral contraceptive use to systemic immune marker profiles: the role of cortisol.Frontiers in endocrinology · 2026Article
- Quantifying chronic stress in group- and stall-housed sows during gestation using cortisol in hair.Animal welfare (South Mimms, England) · 2026Article
- Resilience Mitigates the Link between Adverse Childhood Experiences and Musician's Dystonia: A Neuroendocrine and Psychological Perspective.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- Bidirectional brain-heart communication in coronary heart disease: from coronary plaques to central autonomic networks.Frontiers in neuroscience · 2026Review
- Hair cortisol as psychotherapy process parameter - an inpatient pediatric psychosomatic study.Frontiers in psychiatry · 2026Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewThis review focuses on the concentration of cortisol in human hair as a biomarker of chronic stress in cardiovascular disease (CVD). We outline the cardiovascular consequences of cortisol excess and provide a comprehensive overview of recent studies investigating the relationship of hair cortisol with CVD. In addition, clinical implications and limitations of the evidence are discussed, together with directions for future research. RECENT
findingsHair cortisol may be a reliable biomarker of chronic stress since it provides quantification of total cortisol secreted into hair over several weeks. A growing body of evidence suggests that elevated hair cortisol levels are associated with both the incidence of CVD and poorer recovery and treatment outcomes. Moreover, increased hair cortisol concentration has been linked with established cardiometabolic risk factors for CVD including high blood pressure, diabetes, and adiposity. Hair cortisol is a promising biomarker of chronic cortisol excess which may contribute to both the pathogenesis and prognosis of CVD. However, the current evidence relies on small-scale cross-sectional studies. Further research adopting longitudinal designs across larger samples of CVD patients and healthy participants is required to inform the development of novel evidence-based interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.