ArticleBMJ open2019
The association of exercise and sedentary behaviours with incident end-stage renal disease: the Southern Community Cohort Study.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Sedentary behavior as an emerging risk factor for chronic kidney disease: a narrative review.Clinical and experimental nephrology · 2026Review
- Increased Risk of End-Stage Kidney Disease After Traumatic Amputation: Nationwide Cohort Study.Healthcare (Basel, Switzerland) · 2025Article
- Chronic Kidney Disease Progression-A Challenge.Biomedicines · 2024Review
- The association of sleep duration with the risk of chronic kidney disease: a systematic review and meta-analysis.Clinical kidney journal · 2024Article
- Association of physical activity with risk of chronic kidney disease in China: A population-based cohort study.Journal of sport and health science · 2024Article
- The Moderating Role of Health Variables on the Association between Physical Exercise and Quality of Life in Patients with End-Stage Renal Disease.Healthcare (Basel, Switzerland) · 2023Article
- The Potential Modulatory Effects of Exercise on Skeletal Muscle Redox Status in Chronic Kidney Disease.International journal of molecular sciences · 2023Review
- High physical activity alleviates the adverse effect of higher sedentary time on the incidence of chronic kidney disease.Journal of cachexia, sarcopenia and muscle · 2023Article
- Associations of Prolonged Occupational Sitting with the Spectrum of Kidney Disease: Results from a Cohort of a Half-Million Asian Adults.Sports medicine - open · 2022Article
- End-stage kidney disease in patients with clinically manifest vascular disease; incidence and risk factors: results from the UCC-SMART cohort study.Journal of nephrology · 2021Article
- Advances in exercise therapy in predialysis chronic kidney disease, hemodialysis, peritoneal dialysis, and kidney transplantation.Current opinion in nephrology and hypertension · 2020Review
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo examine whether lifestyle factors, including sedentary time and physical activity, could independently contribute to risk of end-stage renal disease (ESRD). STUDY
designCase-cohort study.
settingSouth-eastern USA.
participantsThe Southern Community Cohort Study recruited ~86 000 black and white participants from 2002 to 2009. We assembled a case cohort of 692 incident ESRD cases and a probability sample of 4113 participants. PREDICTORS: Sedentary time was calculated as hours/day from daily sitting activities. Physical activity was calculated as metabolic equivalent (MET)-hours/day from engagement in light, moderate and vigorous activities. OUTCOMES: Incident ESRD.
resultsAt baseline, among the subcohort, mean (SD) age was 52 (8.6) years, and median (25th, 75th centile) estimated glomerular filtration rate (eGFR) was 102.8 (85.9-117.9) mL/min/1.73 m
conclusionsIn a population with a high prevalence of chronic kidney disease risk factors such as hypertension and diabetes, physical activity appears to be associated with reduced risk of ESRD among those with preserved kidney function. A positive association between sitting time and ESRD observed among those with advanced kidney disease is likely due to reverse causation.
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