Observational studyBMJ open2019
Association between smoking and in-hospital mortality in patients with acute myocardial infarction: results from a prospective, multicentre, observational study in China.
Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01874691 (China Acute Myocardial Infarction Registry), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
China Acute Myocardial Infarction Registry
Who cites it
12 citing papers in PubMed.
- Survival After the First Myocardial Infarction in Older Women: A Prospective Cohort Analysis From the WHI.Journal of the American Heart Association · 2026Article
- A Predictive Nomogram of In-Hospital Mortality After 48 h for Atrial Fibrillation Patients in the Coronary Care Unit.Clinical cardiology · 2024Article
- Smoking and 10-year risk of cardiovascular and non-cardiovascular events after contemporary coronary stenting.American journal of preventive cardiology · 2024Article
- In-Hospital Mortality in Patients With Acute Myocardial Infarction: A Literature Overview.Cureus · 2024Review
- Explainable SHAP-XGBoost models for in-hospital mortality after myocardial infarction.Cardiovascular digital health journal · 2023Article
- Article
- The Erne Mobile Intensive Coronary Care Study : Mortality, survival and MICCU.Irish journal of medical science · 2022Article
- Effects of Smoking on Very-Long Term Mortality after First ST Elevation Myocardial Infarction.Arquivos brasileiros de cardiologia · 2022Article
- Association between smoking and in-hospital mortality in patients with left ventricular dysfunction undergoing coronary artery bypass surgery: a propensity-matched study.BMC cardiovascular disorders · 2021Article
- Effects of Smoking on Long-Term Clinical Outcomes and Lung Cancer in Patients with Acute Myocardial Infarction.Korean circulation journal · 2021Article
- Clopidogrel Resistance in Patients With Stroke Recurrence Under Single or Dual Antiplatelet Treatment.Frontiers in neurology · 2021Article
- Effect of smoking on clinical outcomes in patients receiving rotational atherectomy in calcified coronary lesions: from the ROCK Registry, South Korea.Annals of Saudi medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSmoking is a well-established risk factor for cardiovascular disease. However, the effect of smoking on in-hospital mortality in patients with acute myocardial infarction (AMI) who are managed by contemporary treatment is still unclear.
methodsA cohort study was conducted using data from the China AMI registry between 2013 and 2016. Eligible patients were diagnosed with AMI in accordance with the third universal definition of MI. Propensity score (PS) matching and multivariable logistic regression were used to control for confounders. Subgroup analysis was performed to examine whether the association between smoking and in-hospital mortality varies according to baseline characteristics.
resultsA total of 37 614 patients were included. Smokers were younger and more frequently men with fewer comorbidities than non-smokers. After PS matching and multivariable log regression analysis were performed, the difference in in-hospital mortality between current smokers versus non-smokers was reduced, but it was still significant (5.1% vs 6.1%, p=0.0045; adjusted OR 0.78, 95% CI 0.69 to 0.88, p<0.001). Among all subgroups, there was a trend towards lower in-hospital mortality in current or ex-smokers compared with non-smokers.
conclusionsSmoking is associated with lower in-hospital mortality in patients with AMI, even after multiple analyses to control for potential confounders. This 'smoker's paradox' cannot be fully explained by confounding alone. TRIAL REGISTRATION NUMBER: NCT01874691.
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