Evidence map›Paper›PMID 31471416›Full record

ArticleIn vivo (Athens, Greece)

Strain Ultrasound Elastography in the Achilles Tendon of Ankylosing Spondylitis Patients Treated With Anti-TNF-α: A Preliminary Study.

Enrico M Zardi, Maria Elena Pipita, Chiara Giorgi, Antonella Afeltra, Nicola Maffulli, Francesco Franceschi

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Enrico M ZardiInternistic Ultrasound Service "Campus Bio-Medico" University, Rome, Italy e.zardi@unicampus.it.
Maria Elena PipitaInternistic Ultrasound Service "Campus Bio-Medico" University, Rome, Italy.
Chiara GiorgiRadiology Department, S. Maria della Misericordia Hospital, Urbino, Italy.
Antonella AfeltraImmunorheumatology "Campus Bio-Medico" University, Rome, Italy.
Nicola MaffulliDepartment of Musculoskeletal Disorders, School of Medicine and Surgery, University of Salerno, Salerno, Italy.
Francesco FranceschiDepartment of Orthopaedic and Trauma Surgery, Campus Biomedico University, Rome, Italy.
Università Campus Bio-Medico · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimTo compare patients affected by ankylosing spondylitis (AS) treated with anti-TNF-α for two years with controls in terms of Achilles tendon stiffness, ultrasound structure and thickness. PATIENTS AND

methodsB-mode ultrasound evaluation and strain ultrasound elastography were performed in longitudinal and transverse planes on 22 Achilles tendons of 11 AS patients and 26 of 13 controls.

resultsThere were no significant differences in thickness and stiffness of the Achilles tendon between AS patients and controls, except for an increased thickness in the middle third of the tendon in the AS patients (p=0.04). The Achilles tendon stiffness ratio of AS patients was 1.02±0.36 vs. 1.14±0.38 in the controls (p=0.2).

conclusionAS patients had an Achilles tendon thickness greater than controls at the middle third, but no difference in the stiffness was found among them. Strain ultrasound elastography may be useful to exclude early changes in mechanical properties of tendons.

Indexed as

Elasticity Imaging TechniquesUltrasonographyAchilles TendonAgedAntibodies, MonoclonalCase-Control StudiesFemaleHumansMaleMiddle AgedSpondylitis, AnkylosingTreatment OutcomeTumor Necrosis Factor-alphaAntibodies, MonoclonalTumor Necrosis Factor-alphaAchilles tendonankylosing spondylitisanti-TNF-α therapyelastographyultrasound

Identifiers

PMID31471416
PMCPMC6755005
OpenAlexW2971225629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.