Evidence map›Paper›PMID 31471406›Full record

ReviewIn vivo (Athens, Greece)

Overview and Comparison of Infectious Endocarditis and Non-infectious Endocarditis: A Review of 814 Autoptic Cases.

Rossana Bussani, Fabio DE-Giorgio, Giuliano Pesel, Lorenzo Zandonà, Gianfranco Sinagra, Simone Grassi, Alfonso Baldi, Antonio Abbate, Furio Silvestri

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 56 citations in OpenAlex.

  1. A rare presentation of nonbacterial thrombotic endocarditis.Journal of vascular surgery cases and innovative techniques · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rossana Bussani *Institute of Pathological Anatomy, Riuniti Hospital and University of Trieste, Trieste, Italy.
Fabio DE-Giorgio *Institute of Public Health, Section of Legal Medicine, Università Cattolica del Sacro Cuore, Rome, Italy fabio.degiorgio@unicatt.it.
Giuliano PeselInstitute of Pathological Anatomy, Riuniti Hospital and University of Trieste, Trieste, Italy.
Lorenzo ZandonàInstitute of Pathological Anatomy, Riuniti Hospital and University of Trieste, Trieste, Italy.
Gianfranco SinagraCardiovascular Department, Riuniti Hospital and University of Trieste, Trieste, Italy.
Simone GrassiInstitute of Public Health, Section of Legal Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.
Alfonso BaldiDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies, L. Vanvitelli University of Campania, Caserta, Italy.
Antonio AbbateVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, U.S.A.
Furio SilvestriInstitute of Pathological Anatomy, Riuniti Hospital and University of Trieste, Trieste, Italy.
University of Trieste · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
NCATS NIH HHS UL1 TR002649
6 · The paper itself

Abstract

aimWe examined evidence on infective and non-infective endocarditis obtained from a database of 50,403 clinical autopsies performed at an Italian general hospital between January 1983 and December 2006. MATERIALS AND

methodsOut of 814 endocarditis cases, 409 were of infective endocarditis (IE) and 405 non-infective (NIE). The median age at the time of death was 78 years for those with IE and 83 for those with NIE. Data were collected on gender, clinical history, comorbidities, kind of affected valve (non-prosthetic/mechanical/biological), pathological features of endocarditis, endocarditis complications and microbiological agents.

resultsThe diagnosis of IE was frequently missed and these conditions were often complicated by cardiovascular events. IE was more common among patients with prior valve infection or cardiovascular surgery, while malignancies were frequent comorbidities of NIE.

conclusionIn general, we found several data that differ from those generally present in the scientific literature, and this could be explained by the fact that data on IE and NIE are generally obtained from surgical and clinical databases, while we analysed only autoptic cases.

Indexed as

AgedAged, 80 and overAutopsyDiagnosis, DifferentialEndocarditisEndocarditis, BacterialEndocarditis, Non-InfectiveFemaleHumansMaleMiddle AgedRetrospective Studiesautopsyforensic scienceInfective endocarditisnon-bacterial thrombotic endocarditisnon-infective endocarditispost mortemsudden death

Identifiers

PMID31471406
PMCPMC6755013
OpenAlexW2970325245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.