Evidence map›Paper›PMID 31471355›Full record

ArticleBMJ case reports2019

Novel clinical phenotype of generalised lymphatic dysplasia in a neonate: a missed diagnosis.

Thangaraj Abiramalatha, Thanka Johnson, Umamaheswari Balakrishnan, Prakash Amboiram

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Thangaraj AbiramalathaNeonatology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Thanka JohnsonPathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Umamaheswari BalakrishnanNeonatology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Prakash AmboiramNeonatology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Sri Ramachandra Institute of Higher Education and Research · INScope e-Knowledge Center (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a preterm neonate who had a large cervical cystic hygroma and right chylothorax. She was operated on day-21 and a near-complete resection of cystic hygroma was done. She developed refractory hypoxemia and shock post surgery and died after 24 hours. During autopsy, the chest cavity was found to be filled with chyle. Histopathological examination showed dilated lymphatics in the pleura, hepatic capsule, serosa of stomach and intestines, peri-pancreatic regions, peri-renal capsule and peri-adrenal tissues suggestive of generalised lymphatic dysplasia. Clinical exome sequencing did not reveal any pathogenic mutation in the genes involved in primary lymphatic dysplasia, noonan syndrome or rasopathies.

Indexed as

PhenotypeCervical VertebraeChylothoraxCraniofacial AbnormalitiesDiagnostic ErrorsFatal OutcomeFemaleHumansInfant, NewbornInfant, PrematureLymphangiectasis, IntestinalLymphangioma, CysticLymphedemaSpinal Neoplasmscongenital disordersneonatal healthNeonatal intensive carepaediatric surgery

Identifiers

PMID31471355
PMCPMC6720905
OpenAlexW2970771790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.