SynthesisJournal of orthopaedic surgery and research2019
Effect of intramedullary nail and locking plate in the treatment of proximal humerus fracture: an update systematic review and meta-analysis.
Synthesis in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Locking plates versus intramedullary nails for the treatment of two- and three-part proximal humerus fractures in patients older than 60 years: a meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Pooled it
- Risk factors for osteonecrosis of the humeral head after internal fixation of proximal humeral fractures: a systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2024Pooled it
- Surgical treatment of proximal humerus fractures: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Pooled it
- Interventions for treating proximal humeral fractures in adults.The Cochrane database of systematic reviews · 2022Pooled it
- Interlocking intramedullary nailing versus compression plating in the treatment of humeral fractures: Analysis of shoulder functional recovery, complication rates, and risk factors for reoperation.Pakistan journal of medical sciences · 2026Article
- The ORIN-open reduction and intramedullary nailing-technique for 4-part proximal humerus fractures.JSES reviews, reports, and techniques · 2026Article
- A rotator cuff sparing deltopectoral approach to intramedullary nail of humeral fractures.JSES international · 2026Article
- A cohort study of minimally invasive plate osteosynthesis combined with an enhanced recovery after surgery in the treatment of proximal humeral fractures.Langenbeck's archives of surgery · 2025Article
- Minimally Invasive Treatment of Three-Part Proximal Humerus Fractures: A Two-Center Comparative Study of Plate Fixation and Intramedullary Nailing.Journal of clinical medicine · 2025Article
- Post-operative radiographic evaluation of reduction loss in unstable proximal humerus fractures: a comparative study of intramedullary nails and locking plates in patients over 50 years.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Observational
- Clinical outcomes following intramedullary nailing of humerus fractures: a systematic review.JSES international · 2025Review
- Risk factors associated with secondary displacement in fractures of the humeral greater tuberosity.Frontiers in surgery · 2025Article
- A clinical study on robot navigationassisted intramedullary nail treatment for humeral shaft fractures.BMC musculoskeletal disorders · 2024Article
- Head-Shaft Angle Influences Isometric Shoulder Strength Levels after Intramedullary Nailing of Proximal Humerus Fractures: A Pilot Study.Journal of personalized medicine · 2024Article
- Intramedullary versus locking plate fixation for proximal humerus fractures: indications and technical considerations.JSES reviews, reports, and techniques · 2024Review
- Reverse Shoulder Prosthesis for Proximal Humeral Fractures: Primary Treatment vs. Salvage Procedure.Journal of clinical medicine · 2024Article
- Finite element method analysis of bone stress for variants of locking plate placement.Heliyon · 2024Article
- Review
- Morphology and novel classification of proximal humeral fractures.Frontiers in bioengineering and biotechnology · 2024Article
- Risk Factors and Clinical Outcomes after Antegrade Intramedullary Nailing in Proximal Humeral Fractures: Insights and Implications for Patient Satisfaction.Journal of personalized medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundTo evaluate the effect of intramedullary nail and locking plate in the treatment of proximal humerus fracture (PHF).
methodsChina National Knowledge Infrastructure (CNKI), Chinese Scientific Journals Database (VIP), Wan-fang database, Chinese Biomedicine Database (CBM), PubMed, EMBASE, Web of Science, and Cochrane Library were searched until July 2018. The eligible references all show that the control group uses locking plates to treat PHF, while the experimental group uses intramedullary nails to do that. Two reviewers independently retrieved and extracted the data. Reviewer Manager 5.3 was used for statistical analysis.
resultsThirty-eight retrospective studies were referred in this study which involves 2699 patients. Meta-analysis results show that the intramedullary nails in the treatment of proximal humeral fractures are superior to locking plates in terms of intraoperative blood loss, operative time, fracture healing time, postoperative complications, and postoperative infection. But there is no significance in constant, neck angle, VAS, external rotation, antexion, intorsion pronation, abduction, NEER, osteonecrosis, additional surgery, impingement syndrome, delayed union, screw penetration, and screw back-out.
conclusionsThe intramedullary nail is superior to locking plate in reducing the total complication, intraoperative blood loss, operative time, postoperative fracture healing time and postoperative humeral head necrosis rate of PHF. Due to the limitations in this meta-analysis, more large-scale, multicenter, and rigorous designed RCTs should be conducted to confirm our findings.
trial registrationPROSPERO CRD42019120508.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.