Evidence map›Paper›PMID 31470873›Full record

ArticleMalaria journal2019

Semi-field evaluation of the cumulative effects of a "Lethal House Lure" on malaria mosquito mortality.

Antoine M G Barreaux, Welbeck A Oumbouke, Innocent Zran Tia, N'guessan Brou, Alphonsine A Koffi, Raphaël N'guessan, Matthew B Thomas

Registry-linked trialAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Malaria journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05736679 (EaveTubes for Control of Vector Borne Diseases in Côte d'Ivoire), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05736679 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

EaveTubes for Control of Vector Borne Diseases in Côte d'Ivoire

TypeinterventionalSponsorUniversity of Notre DameRan2023 to 2025Enrolled1,870ConditionsMalariaArmsIn2Care EaveTube
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The role of human and mosquito behaviour in the efficacy of a house-based intervention.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Antoine M G BarreauxDepartment of Entomology, Center for Infectious Disease Dynamics, Pennsylvania State University, University Park, PA, 16802, USA. antoine.barreaux@gmail.com.ORCID http://orcid.org/0000-0001-5822-761X
Welbeck A OumboukeInstitut Pierre Richet/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Innocent Zran TiaInstitut Pierre Richet/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
N'guessan BrouInstitut Pierre Richet/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Alphonsine A KoffiInstitut Pierre Richet/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Raphaël N'guessanInstitut Pierre Richet/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Matthew B ThomasDepartment of Entomology, Center for Infectious Disease Dynamics, Pennsylvania State University, University Park, PA, 16802, USA.

Funding

Agricultural Research Service Accession #1018545.Agricultural Research Service National Institute of Food and Agriculture and Hatch Appropriations under Project #PEN04691Bill and Melinda Gates Foundation OPP1131603
6 · The paper itself

Abstract

backgroundThere is growing interest in the potential to modify houses to target mosquitoes with insecticides or repellents as they search for human hosts. One version of this 'Lethal House Lure' approach is the In2Care

methodsAnopheles gambiae sensu lato mosquitoes were collected from the field as larvae and reared through to adult. Three-to-five days old adult females were released inside an enclosure housing two modified West African style experimental huts at a field site in M'be, Côte d'Ivoire. Huts were either equipped with insecticide-treated tubes at eave height and had closed windows (treatment) or had open windows and open tubes (controls). The number of host-seeking mosquitoes entering the huts and cumulative mortality were monitored over 2 or 4 days.

resultsVery few (0-0.4%) mosquitoes were able to enter huts fitted with insecticide-treated tubes and closed windows. In contrast, mosquitoes continually entered the control huts, with a cumulative mean of 50-80% over 2 to 4 days. Baseline mortality with control huts was approximately 2-4% per day, but the addition of insecticide-treated tubes increased mortality to around 25% per day. Overall cumulative mortality was estimated to be up to 87% over 4 days when huts were fitted with tubes.

conclusionOnly 20-25% of mosquitoes contacted insecticide-treated tubes or entered control huts in a given night. However, mosquitoes continue to host search over sequential nights, and this can lead to high cumulative mortality over 2 to 4 days. This mortality should contribute to community-level reduction in transmission assuming sufficient coverage of the intervention.

Indexed as

InsecticidesAnimalsAnophelesCote d'IvoireFemaleHousingMortalityMosquito ControlMosquito VectorsInsecticidesAnopheles gambiaeCumulative mortalityEaveTubeFeeding rateHousing improvementLethal House LureMosquito entryScreeningVector control

Identifiers

PMID31470873
PMCPMC6716835

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.