Evidence map›Paper›PMID 31470859›Full record

SynthesisEnvironmental health : a global access science source2019

Asbestos exposure and malignant mesothelioma of the tunica vaginalis testis: a systematic review and the experience of the Apulia (southern Italy) mesothelioma register.

Luigi Vimercati, Domenica Cavone, Maria Celeste Delfino, Luigi De Maria, Antonio Caputi, Giovanni Maria Ferri, Gabriella Serio

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Environmental health : a global access science source, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

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  12. [Occupational cancers in urology].Der Urologe. Ausg. A · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Luigi VimercatiInterdisciplinary Department of Medicine (DIM), Unit of Occupational Medicine, Section Occupational Medicine. "B. Ramazzini", University Aldo Moro of Bari Medical School, 11 G. Cesare Square, 70124, Bari, Italy. luigi.vimercati@uniba.it.ORCID http://orcid.org/0000-0002-4072-2871
Domenica CavoneInterdisciplinary Department of Medicine (DIM), Unit of Occupational Medicine, Section Occupational Medicine. "B. Ramazzini", University Aldo Moro of Bari Medical School, 11 G. Cesare Square, 70124, Bari, Italy.
Maria Celeste DelfinoInterdisciplinary Department of Medicine (DIM), Unit of Occupational Medicine, Section Occupational Medicine. "B. Ramazzini", University Aldo Moro of Bari Medical School, 11 G. Cesare Square, 70124, Bari, Italy.
Luigi De MariaInterdisciplinary Department of Medicine (DIM), Unit of Occupational Medicine, Section Occupational Medicine. "B. Ramazzini", University Aldo Moro of Bari Medical School, 11 G. Cesare Square, 70124, Bari, Italy.
Antonio CaputiInterdisciplinary Department of Medicine (DIM), Unit of Occupational Medicine, Section Occupational Medicine. "B. Ramazzini", University Aldo Moro of Bari Medical School, 11 G. Cesare Square, 70124, Bari, Italy.
Giovanni Maria FerriInterdisciplinary Department of Medicine (DIM), Unit of Occupational Medicine, Section Occupational Medicine. "B. Ramazzini", University Aldo Moro of Bari Medical School, 11 G. Cesare Square, 70124, Bari, Italy.
Gabriella SerioDepartment of Emergency and Organ Transplantation (DETO), Pathology Division, University Aldo Moro of Bari Medical School, 11 G. Cesare Square, 70124, Bari, Italy.
University of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalignant mesothelioma of the tunica vaginalis testis (MMTVT) is a rare disease with a poor prognosis. The diagnosis and management of these lesions are often difficult for pathologists, surgeons, oncologists and occupational physicians. A preoperative diagnosis of malignancy is rarely made, and there is no established effective therapy except orchidectomy.

methodsA systematic literature review was conducted among the articles published in the English literature on primary MMTVT. Moreover four cases from the Apulia mesothelioma register are reported here.

resultsTwo hundred eighty-nine cases of MMTVT have been reported from 1943 to 2018. Overall asbestos exposure has been investigated only for 58% of all cases reported in this review, while in 41.8% this data are not available. Noteworthy is the fact that in many reports there is not an anamnestic reconstruction of any asbestos exposure. A history of direct occupational, environmental or familial asbestos exposure is found in 27.6% of the cases. The four cases from the Apulia mesothelioma register are all with ascertained occupational exposure to asbestos.

conclusionsThe true incidence of asbestos exposure in MMTVT is underestimated because of insufficient information reported in older literature. To establish a broad consensus on the causal relationship between asbestos and MMTVT in the scientific community its necessary to analyze the same variables in the epidemiological studies. In general it should be recommended that a positive history of exposure to asbestos or to asbestos-containing materials are at risk for the development of a MMTVT and should be monitored.

Indexed as

AsbestosHumansIncidenceItalyLung NeoplasmsMaleMesotheliomaMesothelioma, MalignantOccupational DiseasesOccupational ExposureRegistriesTesticular NeoplasmsAsbestosApulia southern ItalyAsbestosMesotheliomaMesothelioma registerReviewTunica vaginalis

Identifiers

PMID31470859
PMCPMC6717382
OpenAlexW2971329026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.