Evidence map›Paper›PMID 31470845›Full record

ArticleBMC musculoskeletal disorders2019

Correlational analysis between neutrophil granulocyte levels and osteonecrosis of the femoral head.

Jiang Jiang, Xuqiang Liu, Baojian Lai, Dengjiong Hu, Lizhen Lai, Jiaxiang Xu, Songqing Chen, Xiaofeng Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  8. Clinical Characteristics, Current Treatment Options, Potential Mechanisms, Biomarkers, and Therapeutic Targets in Avascular Necrosis of Femoral Head.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024
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  13. [Research progress of immune cells regulating the occurrence and development of osteonecrosis of the femoral head].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jiang JiangDepartment of Orthopedics, the First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, No. 17 Yongwaizheng Street, Nanchang City, Jiangxi Province, China.
Xuqiang LiuDepartment of Orthopedics, the First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, No. 17 Yongwaizheng Street, Nanchang City, Jiangxi Province, China.
Baojian LaiDepartment of Orthopedics, the First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, No. 17 Yongwaizheng Street, Nanchang City, Jiangxi Province, China.
Dengjiong HuDepartment of Orthopedics, the First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, No. 17 Yongwaizheng Street, Nanchang City, Jiangxi Province, China.
Lizhen LaiDepartment of Orthopedics, the First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, No. 17 Yongwaizheng Street, Nanchang City, Jiangxi Province, China.
Jiaxiang XuDepartment of Orthopedics, the First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, No. 17 Yongwaizheng Street, Nanchang City, Jiangxi Province, China.
Songqing ChenDepartment of Orthopedics, the First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, No. 17 Yongwaizheng Street, Nanchang City, Jiangxi Province, China.
Xiaofeng LiDepartment of Orthopedics, the First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, No. 17 Yongwaizheng Street, Nanchang City, Jiangxi Province, China. Doublejiang9@163.com.
First Affiliated Hospital of Nanchang University · CNNanchang University · CN

Funding

5511 Science and Technology Innovation Talent Project of Jiangxi Province 20171BAB205033National Foundation for Science and Technology Development 81601912
6 · The paper itself

Abstract

backgroundThe correlation between peripheral blood neutrophil level and osteonecrosis of the femoral head (ONFH) has not been extensively studied. Thus, we aimed to investigate the correlation between neutrophil level in the peripheral blood (neutrophil granulocyte) and ONFH.

methodsA total of 984 cases of ONFH and femoral neck fractures (non-ONFH) diagnosed at the Department of Orthopedics at our institution between January 1, 2011 and December 31, 2016 were retrospectively reviewed. The ONFH and non-ONFH groups comprised 488 and 496 cases, respectively. Basic information and peripheral blood cell levels of the two groups were compared.

resultsThe patients' mean age was 59.89 ± 17.06 years (range: 38-82 years). There were 457 male and 527 female patients, with a male-to-female ratio of 1:1.15. We found that neutrophil granulocyte levels and percentage of neutrophil granulocytes were significantly different between the ONFH and non-ONFH groups. Multimodal regression analysis showed that the percentage of neutrophil granulocytes was an independent protective factor against ONFH.

conclusionsThe factors influencing ONFH are neutrophil granulocyte levels and percentage of neutrophil granulocytes. Percentage of neutrophil granulocytes has a significant correlation with aseptic femoral head necrosis, providing a new perspective and direction for further study of femoral head necrosis.

Indexed as

NeutrophilsAdultAgedAged, 80 and overCase-Control StudiesFemaleFemoral Neck FracturesFemur Head NecrosisHumansLeukocyte CountMaleMiddle AgedRetrospective StudiesBone repairFemoral head necrosisInfluencing factorNeutrophilOsteonecrosis

Identifiers

PMID31470845
PMCPMC6717348
OpenAlexW2970072613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.