Evidence map›Paper›PMID 31470796›Full record

Trial reportBMC anesthesiology2019

Effect of endotracheal tube lubrication on cuff pressure increase during nitrous oxide exposure: a laboratory and prospective randomized controlled trial.

Moriyoshi Oji, Yukihide Koyama, Hiroyuki Oshika, Masashi Kohno, Yusuke Nakahashi, Sayano Fukushima, Hidemasa Iwakura, Tomio Andoh

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Comparing leak pressure of LMACanadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Moriyoshi OjiDepartment of Anesthesia, Tomei Atsugi Hospital, Atsugi, Japan.
Yukihide KoyamaDepartment of Anesthesia, Tomei Atsugi Hospital, Atsugi, Japan. yukihidekoyama1008@gmail.com.ORCID 0000-0002-5975-2579
Hiroyuki OshikaDepartment of Anesthesia, Tomei Atsugi Hospital, Atsugi, Japan.
Masashi KohnoDepartment of Anesthesia, Tomei Atsugi Hospital, Atsugi, Japan.
Yusuke NakahashiDepartment of Anesthesia, Tomei Atsugi Hospital, Atsugi, Japan.
Sayano FukushimaDepartment of Anesthesia, Tomei Atsugi Hospital, Atsugi, Japan.
Hidemasa IwakuraDepartment of Anesthesia, Tomei Atsugi Hospital, Atsugi, Japan.
Tomio AndohDepartment of Anesthesiology, Mizonokuchi Hospital, Teikyo University School of Medicine, 5-1-1 Futako, Takatsu-ku, Kawasaki, Kanagawa Prefecture, 213-8507, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe previously demonstrated that lubrication of an endotracheal tube (ETT) cuff with K-Y™ jelly strongly and significantly inhibited the increase in cuff pressure during nitrous oxide (N

methodsWe first sought to study how changes in the amount of K-Y™ jelly and temperature influence the inhibitory effects of the lubricant on the increase in N

resultsIn the laboratory studies, we found that K-Y™ jelly inhibited the cuff pressure increase dose-dependently when the dose of K-Y™ jelly was varied (P = 0.02), and that such an inhibitory effect decreased with an increase in the studied temperature (P = 0.019). In the clinical study, lubrication with K-Y™ jelly slightly, but significantly, delayed the increase in ETT cuff pressure during general anesthesia with N

conclusionsLubrication of the ETT cuff with K-Y™ jelly may delay the increase in cuff pressure during general anaesthesia with N

trial registrationUMIN Clinical Trials Registry: UMIN000031377 on March 1, 2019.

Indexed as

LubricationPressureSurgical EquipmentCelluloseDose-Response Relationship, DrugFemaleGlycerolHumansIntubation, IntratrachealIn Vitro TechniquesMaleMiddle AgedNitrous OxidePhosphatesPropylene GlycolsTemperatureCelluloseGlycerolK-Y jellyNitrous OxidePhosphatesPropylene GlycolsCuff pressure increaseEndotracheal tube cuffK-Y™ jellyLubricationNitrous oxide diffusion

Identifiers

PMID31470796
PMCPMC6717381

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.