Evidence map›Paper›PMID 31470661›Full record

ReviewPolymers2019

Applications of Hydrogels with Special Physical Properties in Biomedicine.

Gong Chen, Wenwei Tang, Xiaohui Wang, Xueling Zhao, Cheng Chen, Zhigang Zhu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 114 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gong ChenSchool of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China.
Wenwei TangModern Service Department, College of International Vocational Education, Shanghai Polytechnic University, Shanghai 201209, China.
Xiaohui WangSchool of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China.
Xueling ZhaoSchool of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China.
Cheng ChenSchool of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China. chencheng@sspu.edu.cn.
Zhigang ZhuSchool of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China. zgzhu@sspu.edu.cn.
Shanghai Polytechnic University · CN

Funding

Chenguang project supported by Shanghai Municipal Education Commission 18CG68National Natural Science Foundation of China 61471233, 21504051Sailing Project from Science and Technology Commission of Shanghai Municipality 17YF1406600
6 · The paper itself

Abstract

As a polymer matrix containing a large amount of water, hydrogels have been widely used in many fields such as biology and medicine due to its similarity to extracellular matrix components, and its contact with blood, body fluids, and human tissue does not affect the metabolic processes of living organisms. However, due to the lack of unique physical properties of traditional polymer hydrogels, its further application in the high-end field is limited. With the progress of study, a series of hydrogels with special structures, such as double network hydrogel, composite hydrogel, Tetra-PEG gel, and topological gel, have improved the situation to a large extent. At the same time, the progress of research on the biocompatibility and biodegradability of hydrogels, which are expected to be used in biomedical fields, is also worthy of attention. This review introduces four such types of high-strength polymeric hydrogels and the mechanisms for improving their mechanical strength. Moreover, a discussion will be made around specific methods for imparting special physical properties to hydrogels and applications in the field of biomedicine such as cell culture, medical surgery, tissue engineering, and biosensing. At the end of the review, the main reasons and contradictions for the limits of the current applications are explained. An outlook on the future research in related fields and the importance of carrying out research in this area to promote medical progress are emphasized.

Indexed as

biomedicinehydrogelphysical properties

Identifiers

PMID31470661
PMCPMC6780509
OpenAlexW2971178217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.