Evidence map›Paper›PMID 31470638›Full record

ArticleMolecules (Basel, Switzerland)2019

Effects of Polar Steroids from the Starfish

Olesya S Malyarenko, Timofey V Malyarenko, Alla A Kicha, Natalia V Ivanchina, Svetlana P Ermakova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Research on the mechanisms of natural products in radiation protection.Frontiers in bioengineering and biotechnology · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Unusual Polyhydroxylated Steroids from the StarfishMolecules (Basel, Switzerland) · 2020
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Olesya S MalyarenkoG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia. malyarenko.os@gmail.com.ORCID 0000-0002-3262-0373
Timofey V MalyarenkoG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.
Alla A KichaG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.
Natalia V IvanchinaG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.
Svetlana P ErmakovaG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 100-let Vladivostok Ave., 690022 Vladivostok, Russia.
Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences · RUFar Eastern Federal University · RU

Funding

Российский Фонд Фундаментальных Исследований (РФФИ) 18-34-20013
6 · The paper itself

Abstract

Despite significant advances in the understanding, prevention, and treatment of cancer, the disease continues to affect millions of people worldwide. Chemoradiation therapy is a rational approach that has already proven beneficial for several malignancies. However, the existence of toxicity to normal tissue is a serious limitation of this treatment modality. The aim of the present study is to investigate the ability of polar steroids from starfish

Indexed as

Gene Expression Regulation, NeoplasticAnimalsAntineoplastic AgentsApoptosisAsterinabcl-2-Associated X Proteinbcl-X ProteinCaspase 3Caspase 9Cell Line, TumorCombined Modality TherapyHCT116 CellsHT29 CellsHumansPolycyclic CompoundsRadiation-Sensitizing AgentsAntineoplastic AgentsBAX protein, humanbcl-2-Associated X ProteinBCL2L1 protein, humanbcl-X ProteinCASP3 protein, humanCASP9 protein, humanCaspase 3Caspase 9Polycyclic CompoundsRadiation-Sensitizing AgentsSaponinsapoptosiscolony formationcolorectal carcinoma cellsDNA fragmentationPatiria (=Asterina) pectiniferapolar steroidsstarfishX-ray

Identifiers

PMID31470638
PMCPMC6749381
OpenAlexW2970422296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.