Evidence map›Paper›PMID 31470587›Full record

ArticleInternational journal of molecular sciences2019

Comparative Quantitative Analysis of Porcine Optic Nerve Head and Retina Subproteomes.

Sebastian Funke, Carsten Schmelter, Sascha D Markowitsch, Natarajan Perumal, Janis C Heyne, Katharina Bell, Norbert Pfeiffer, Franz H Grus

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Mass spectrometry-based retina proteomics.Mass spectrometry reviews · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sebastian FunkeExperimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Carsten SchmelterExperimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.ORCID 0000-0001-7530-690X
Sascha D MarkowitschDepartment of Urology and Pediatric Urology, University Medical Center, 55131 Mainz, Germany.
Natarajan PerumalExperimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.ORCID 0000-0002-2612-5907
Janis C HeyneExperimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Katharina BellExperimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Norbert PfeifferExperimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Franz H GrusExperimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany. fgrus@eye-research.org.
Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optic nerve head (ONH) and retina (RET) are the main sites of damage in neurodegenerative optic neuropathies including glaucoma. Up to date, little is known about the molecular interplay between these two adjoining ocular components in terms of proteomics. To close this gap, we investigated ONH and RET protein extracts derived from porcine eyes (

Indexed as

AnimalsGene OntologyHumansOptic DiskProtein BindingProtein Interaction MapsProteomeProteomicsRetinaSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationSus scrofaTandem Mass SpectrometryProteomeglaucomaLC-MSMALDI-TOF MSoptic nerve headretinaSus scrofa domestica

Identifiers

PMID31470587
PMCPMC6747248
OpenAlexW2970022413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.