ArticleMolecules (Basel, Switzerland)2019
Derivatization of Natural Compound β-Pinene Enhances Its In Vitro Antifungal Activity against Plant Pathogens.
Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- SAR and QSAR Studies of Citral-Based Derivatives Against Colletotrichum fructicola.Chemistry & biodiversity · 2026Article
- Protium heptaphyllum, a tree native to the Atlantic Forest, is a potential source of compounds against important cocoa phytopathogen.Scientific reports · 2026Article
- Essential oil production from seeds of carrot (Daucus carota L.) grown on phytomanaged trace element-contaminated soils.Environmental science and pollution research international · 2026Article
- Design, synthesis and antifungal evaluation of perillaldehyde derivatives as potential laccase inhibitors.Molecular diversity · 2026Article
- Biological Activity of Monoterpene-Based Scaffolds: A Natural Toolbox for Drug Discovery.Molecules (Basel, Switzerland) · 2025Review
- Article
- Anticancer and Antiphytopathogenic Activity of Fluorinated Isatins and Their Water-Soluble Hydrazone Derivatives.International journal of molecular sciences · 2023Article
- The pinene scaffold: its occurrence, chemistry, synthetic utility, and pharmacological importance.RSC advances · 2022Review
- GC-MS Profiling,Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Bioactive Molecules of Mandarin Seed Oils Diminish Mycotoxin and the Existence of Fungi.Molecules (Basel, Switzerland) · 2021Article
- Design, Synthesis, Antibacterial, Antifungal and Anticancer Evaluations of NovelInternational journal of molecular sciences · 2021Article
- Weathering of Antibacterial Melt-Spun Polyfilaments Modified by Pine Rosin.Molecules (Basel, Switzerland) · 2021Article
- Soybean Cyst Nematodes Influence Aboveground Plant Volatile Signals Prior to Symptom Development.Frontiers in plant science · 2021Article
- Essential Oils of Lamiaceae Family Plants as Antifungals.Biomolecules · 2020Review
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Authors and funding
8 authors.
Funding
Abstract
backgroundThe development of new antifungal agents has always been a hot research topic in pesticide development. In this study, a series of derivatives of natural compound β-pinene were prepared, and the antifungal activities of these derivatives were evaluated. The purpose of this work is to develop some novel molecules as promising new fungicides.
methodsThrough a variety of chemical reactions, β-pinene was transformed into a series of β-pinene-based derivatives containing amide moieties and acylthiourea moieties. The antifungal activities of these derivatives against five plant pathogens including
resultsSome derivatives exhibited moderate or significant antifungal activity due to the fusion of the amide moiety or the acylthiourea moiety with the pinane skeleton. The structure-activity relationship analysis showed that the fluorine atom and the strong electron withdrawing nitro group, or trifluoromethyl group on the benzene ring of the derivatives had a significant effect on the improvement of the antifungal activity against
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