Evidence map›Paper›PMID 31470553›Full record

ArticleMolecules (Basel, Switzerland)2019

Converging Fate of the Oxidation and Reduction of 8-Thioguanosine.

Katarzyna Taras-Goslinska, Fabrizio Vetica, Sebastián Barata-Vallejo, Virginia Triantakostanti, Bronisław Marciniak, Chryssostomos Chatgilialoglu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Biomimetic Radical Chemistry and Applications.Molecules (Basel, Switzerland) · 2022
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katarzyna Taras-GoslinskaAdam Mickiewicz University, Faculty of Chemistry, Wieniawskiego 1, 61-712 Poznań, Poland.
Fabrizio VeticaR&D Laboratory, Lipinutragen srl, Via Piero Gobetti 101, 40129 Bologna, Italy.ORCID 0000-0002-7171-8779
Sebastián Barata-VallejoISOF, Consiglio Nazionale delle Ricerche, Via Piero Gobetti 101, 40129 Bologna, Italy.
Virginia TriantakostantiISOF, Consiglio Nazionale delle Ricerche, Via Piero Gobetti 101, 40129 Bologna, Italy.
Bronisław MarciniakAdam Mickiewicz University, Faculty of Chemistry, Wieniawskiego 1, 61-712 Poznań, Poland.
Chryssostomos ChatgilialogluR&D Laboratory, Lipinutragen srl, Via Piero Gobetti 101, 40129 Bologna, Italy. chrys@isof.cnr.it.ORCID 0000-0003-2626-2925

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thione-containing nucleobases have attracted the attention of the scientific community for their application in oncology, virology, and transplantology. The detailed understanding of the reactivity of the purine derivative 8-thioguanosine (8-TG) with reactive oxygen species (ROS) and free radicals is crucial for its biological relevance. An extensive investigation on the fate of 8-TG under both reductive and oxidative conditions is here reported, and it was tested by employing steady-state photooxidation, laser flash photolysis, as well as γ-radiolysis in aqueous solutions. The characterization of the 8-TG T

Indexed as

GuanosineKineticsLasersLightOxidation-ReductionPhotolysisPulse RadiolysisSinglet OxygenSolutionsThionucleosidesWater8-thioguanosineGuanosineSinglet OxygenSolutionsThionucleosidesWaterfree radicalslaser flash photolysisnucleosidesphotolysisreaction mechanismsinglet oxygenγ-radiolysis

Identifiers

PMID31470553
PMCPMC6749358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.