Evidence map›Paper›PMID 31470524›Full record

ArticleMaterials (Basel, Switzerland)2019

Effects of Substrate-Coating Materials on the Wound-Healing Process.

Jin-Young Lin, Kai-Yin Lo, Yung-Shin Sun

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jin-Young LinDepartment of Physics, Fu-Jen Catholic University, New Taipei City 24205, Taiwan.
Kai-Yin LoDepartment of Agricultural Chemistry, National Taiwan University, Taipei 10617, Taiwan.
Yung-Shin SunDepartment of Physics, Fu-Jen Catholic University, New Taipei City 24205, Taiwan. 089957@mail.fju.edu.tw.ORCID 0000-0002-7513-0251
Fu Jen Catholic University · TWNational Taiwan University · TW

Funding

Ministry of Science and Technology, Taiwan MOST 106-2112-M-030-001-MY2Ministry of Science and Technology, Taiwan MOST 107-2221-E-030-001-MY2
6 · The paper itself

Abstract

The wound-healing assay is commonly and widely used for investigating collective cell migration under various physical and chemical stimuli. Substrate-coating materials are shown to affect the wound-healing process in a cell-type dependent manner. However, experiment-to-experiment variations make it difficult to compare results from different assays. In this paper, a modified barrier wound-healing assay was reported for studying the wound-healing process on different substrates in one single petri dish. In short, half of a dish was covered with the tape, and coating materials, poly-l-lysine and gelatin, were applied to the surface. After peeling off the tape, half of the surface was coated with the desired material. Then a customized barrier was placed inside the dish to create the wound. The results indicated that surface coating did not affect cell proliferation/viability, and the wound-healing rate increased in coated surfaces compared to uncoated ones. The present study provides a platform for further understanding the mechanisms of substrate coating-dependent wound-healing processes.

Indexed as

cell migrationfibroblastssurface coatingwound-healing assaywound-healing rate

Identifiers

PMID31470524
PMCPMC6747784
OpenAlexW2970998011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.