ReviewCurrent opinion in immunology2019
Interactions between environmental pollutants and genetic susceptibility in asthma risk.
Review in Current opinion in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Achieving Precision Medicine in Allergic Disease: Progress and Challenges.Frontiers in immunology · 2021Pooled it
- Identifying predictor factors for asthma using machine learning: evidence from the English Longitudinal Study of Ageing.BMC public health · 2026Article
- A Narrative Review of Gene-Environment Interactions in Pediatric Pulmonology.Pediatric pulmonology · 2026Review
- The biodiversity theory of allergy: childhood exposure to natural environments and allergy risk.Annals of medicine and surgery (2012) · 2026Article
- Intra- and inter-multi-omics interaction analysis using deep learning.Bioinformatics advances · 2026Article
- Exploring the epigenetic mechanisms of recurrent pregnancy loss: from genetic predisposition to environmental influences.Journal of assisted reproduction and genetics · 2025Review
- Association between outdoor and indoor air pollutant exposure and depression among middle-aged and older adults in China.Scientific reports · 2025Article
- Advancing translational exposomics: bridging genome, exposome and personalized medicine.Human genomics · 2025Review
- Worldwide Heterogeneity of Food Allergy: Focus on Peach Allergy in Southern Italy.Journal of clinical medicine · 2024Review
- Factors associated with self-reported diagnosed asthma in urban and rural Malawi: Observations from a population-based study of non-communicable diseases.PLOS global public health · 2024Article
- Association of genetic risk and lifestyle with incident adult-onset asthma in the UK Biobank cohort.ERJ open research · 2023Article
- Gene-environment interactions and their impact on human health.Genes and immunity · 2023Review
- Relationship between meteorological and environmental factors and acute exacerbation for pediatric bronchial asthma: Comparative study before and after COVID-19 in Suzhou.Frontiers in public health · 2023Article
- Vitamin D status, sleep patterns, genetic susceptibility, and the risk of incident adult-onset asthma: a large prospective cohort study.Frontiers in nutrition · 2023Article
- Effects of pain and depression on the relationship between household solid fuel use and disability among middle-aged and older adults.Scientific reports · 2022Article
- Air, Land, and Sea: Gene-Environment Interaction in Chronic Disease.The American journal of medicine · 2021Review
- Targeted resequencing showing novel common and rare genetic variants increases the risk of asthma in the Chinese Han population.Journal of clinical laboratory analysis · 2021Article
- Genetics of Food Allergy.Immunology and allergy clinics of North America · 2021Review
- Environmental Determinants of Coronavirus Disease 2019 (COVID-19).Current allergy and asthma reports · 2021Review
- Association of a four-gene model with allergic diseases: Two-year follow-up of a birth cohort study.Immunity, inflammation and disease · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Exposure to air pollution is associated with enhanced risk of developing asthma, notably in the presence of genetic risk factors. Interaction analyses have shown that both outdoor and indoor air pollution interact with genetic variability to increase the incidence of asthma. In this review, we summarize recent progress in candidate gene-based studies, as well as genome-wide gene-air pollution interaction studies. Advances in epigenetics have provided evidence for DNA methylation as a mediator in gene-air pollution interactions. Emerging strategies for study design and statistical analyses may improve power in future studies. Improved air pollution exposure assessment methods and asthma endo-typing can also be expected to increase the ability to detect biologically driven gene-air pollution interaction effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.