Evidence map›Paper›PMID 31470035›Full record

ArticleThe Journal of allergy and clinical immunology2019

IL-12/IL-23 neutralization is ineffective for alopecia areata in mice and humans.

Luana S Ortolan, Sa Rang Kim, Sydney Crotts, Lucy Y Liu, Brittany G Craiglow, Carlos Wambier, Renato S Paschoal, Brett A King, Ali Jabbari

Open access · greenAbstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Treatment of pediatric alopecia areata: A systematic review.Journal of the American Academy of Dermatology · 2022
    Pooled it
  2. Review
  3. Review
  4. Alopecia Areata: Current Treatments and New Directions.American journal of clinical dermatology · 2023
    Review
  5. Article
  6. Virtual memory is a big hairy deal.Nature immunology · 2023
    Article
  7. Review
  8. Recent advances in the genetics of alopecia areata.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2023
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Luana S OrtolanDepartment of Dermatology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Sa Rang KimYale School of Medicine, New Haven, Conn.
Sydney CrottsDepartment of Dermatology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Lucy Y LiuYale School of Medicine, New Haven, Conn.
Brittany G CraiglowDepartment of Dermatology, Yale University, New Haven, Conn; Dermatology Physicians of Connecticut, Fairfield, Conn.
Carlos WambierDepartment of Dermatology, Yale University, New Haven, Conn.
Renato S PaschoalDivision of Dermatology, Department of Internal Medicine, Ribeirao Preto School of Medicine, University of São Paulo, Ribeirao Preto, Brazil.
Brett A KingYale School of Medicine, New Haven, Conn. Electronic address: brett.king@yale.edu.
Ali JabbariDepartment of Dermatology, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Interdisciplinary Program in Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Holden Comprehensive Cancer Center, Carver College of Medicine, University of Iowa, Iowa City, Iowa. Electronic address: ali-jabbari@uiowa.edu.
Yale University · USUniversity of Iowa · USUniversidade de São Paulo · BR

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
Defining T helper cell associated cytokines and mechanisms in Alopecia AreataK08AR069111 · NIAMS · UNIVERSITY OF IOWA · PI JABBARI, ALI · 2016 to 2020
$854k
NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA086862NIAMS NIH HHS K08 AR069111
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AlopeciaAnimalsAntibodies, NeutralizingFemaleHumansInterleukin-12 Subunit p40Interleukin-23 Subunit p19MaleMiceAntibodies, NeutralizingIL12B protein, humanIl12b protein, mouseIL23A protein, humanIl23a protein, mouseInterleukin-12 Subunit p40Interleukin-23 Subunit p19

Identifiers

PMID31470035
PMCPMC6900443
OpenAlexW2971013249

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.