Evidence map›Paper›PMID 31470021›Full record

ArticlePharmacology, biochemistry, and behavior2019

Acute and chronic interactive treatments of serotonin 5HT

Blair K A Willette, Anica Nangia, Sarah Howard, Devon DiPalma, Collin McMillan, Sonum Tharwani, Janequia Evans, Corinne Wells, Susan Slade, Brandon J Hall and 2 more

Open access · greenAbstract read
In one paragraph

Article in Pharmacology, biochemistry, and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Blair K A WilletteDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Anica NangiaDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Sarah HowardDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Devon DiPalmaDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Collin McMillanDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Sonum TharwaniDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Janequia EvansDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Corinne WellsDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Susan SladeDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Brandon J HallDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Amir H RezvaniDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA.
Edward D LevinDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, USA. Electronic address: edlevin@duke.edu.
Duke Medical Center · USDuke University Hospital · US

Funding

Recruitment CoreP50DA027840 · NIDA · DUKE UNIVERSITY · PI DAVIS, JAMES M · 2010 to 2019
$14.9M
NIDA NIH HHS P50 DA027840
6 · The paper itself

Abstract

A variety of neural systems are involved in the brain bases of tobacco addiction. Animal models of nicotine addiction have helped identify a variety of interacting neural systems involved in the pathophysiology of tobacco addiction. We and others have found that drug treatments affecting many of those neurotransmitter systems significantly decrease nicotine self-administration. These treatments include dopamine D

Indexed as

Self AdministrationAnimalsBenzazepinesFemaleNicotineRatsRats, Sprague-DawleyReceptors, Dopamine D1Receptor, Serotonin, 5-HT2CTobacco Use DisorderBenzazepineslorcaserinNicotineReceptors, Dopamine D1Receptor, Serotonin, 5-HT2CSCH 23390AddictionLorcaserinNicotineRatsSCH-23390Self-administration

Identifiers

PMID31470021
PMCPMC6801037
OpenAlexW2970222040

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.