Evidence map›Paper›PMID 31469840›Full record

SynthesisPloS one2019

The effects of action observation training on improving upper limb motor functions in people with stroke: A systematic review and meta-analysis.

Bingbing Zhang, Laidi Kan, Anqin Dong, Jiaqi Zhang, Zhongfei Bai, Yi Xie, Qianhao Liu, Yuzhong Peng

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06196229 (Effects of Action Observation Therapy Based on Virtual Reality for Upper Extremity Rehabilitation in Stroke), which is not on this map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06196229 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effects of Action Observation Therapy Based on Virtual Reality for Upper Extremity Rehabilitation in Stroke

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2024Enrolled36ConditionsStrokeArmsAction Observation Therapy, Action Observation Therapy combined with Virtual Reality
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Action observation for upper limb rehabilitation after stroke.The Cochrane database of systematic reviews · 2022
    Pooled it
  4. Pooled it
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  7. Quo Vadis, Amadeo Hand Robot? A Randomized Study with a Hand Recovery Predictive Model in Subacute Stroke.International journal of environmental research and public health · 2022
    Trial
  8. Article
  9. Visual stimulation in automated gait rehabilitation for post-stroke patients.Frontiers in bioengineering and biotechnology · 2026
    Article
  10. Article
  11. Article
  12. Stimulus specificity in combined action observation and motor imagery of typing.Quarterly journal of experimental psychology (2006) · 2025
    Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bingbing ZhangDepartment of Rehabilitation Medicine, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Laidi KanDepartment of Rehabilitation Medicine, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Anqin DongDepartment of Rehabilitation Medicine, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0000-0003-1084-6184
Jiaqi ZhangDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China.
Zhongfei BaiDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China.
Yi XieDepartment of Rehabilitation Engineering, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Qianhao LiuDepartment of Rehabilitation Medicine, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yuzhong PengDepartment of Rehabilitation Medicine, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveAction observation training (AOT) has been used as a new intervention for improving upper limb motor functions in people with stroke. This systematic review and meta-analysis aims to investigate the effects of AOT on improving upper limb motor functions in people with stroke.

methodsWe searched ten electronic databases to identify randomized controlled trials (RCTs) about the effects of AOT on upper limb motor functions in stroke survivors. Methodological quality of included studies was assessed by the Risk of Bias Tool in the Cochrane Handbook for Systematic Reviews of Interventions. A random-effects meta-analysis was performed by pooling the standardized mean difference (SMD) of upper limb motor outcomes.

resultsSeven studies of 276 participants with stroke were included. Meta-analysis showed a significant effect favoring AOT on improving upper limb motor functions in patients with stroke [SMD = 0.35, 95% confidence interval [CI], 0.10 to 0.61, I2 = 10.14%, p = 0.007].

conclusionsAOT appears to be an effective intervention for improving the upper limb motor functions in people after stroke. Further studies need to investigate the neural mechanism underlying the effects of AOT.

Indexed as

Stroke RehabilitationActivities of Daily LivingFemaleHumansMaleMotor ActivityRecovery of FunctionStrokeUpper Extremity

Identifiers

PMID31469840
PMCPMC6716645

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.